NCT06131710

Brief Summary

This research study aims to compare the effectiveness of two different exercise approaches in treating Patellofemoral Pain Syndrome (PFPS) in basketball players. It employs a randomized clinical trial with 32 participants aged 18-40 diagnosed with PFPS. The participants are divided into two groups: Isolated Strengthening Exercises (ISE) and Combined Strengthening Exercises (CSE). The ISE group focuses solely on quadriceps strengthening exercises, while the CSE group incorporates both quadriceps and proximal strengthening exercises for the hip and core muscles. Outcome measures include pain levels, functionality, and physical performance assessments recorded at baseline and after 6 weeks. Statistical analysis using independent t-tests in SPSS will determine which approach is more effective. This study seeks to provide evidence on whether the combination of proximal strengthening exercises enhances the reduction of pain and improvement in functionality for basketball players with PFPS, compared to isolated strengthening exercises alone.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
32

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 5, 2023

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

November 9, 2023

Completed
5 days until next milestone

First Posted

Study publicly available on registry

November 14, 2023

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 5, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 5, 2024

Completed
Last Updated

January 30, 2024

Status Verified

January 1, 2024

Enrollment Period

9 months

First QC Date

November 9, 2023

Last Update Submit

January 28, 2024

Conditions

Patellofemoral Syndrome

Keywords

ClamshellIsolated exercisePainPatellofemoral syndromeSquat

Outcome Measures

Primary Outcomes (3)

  • Numeric pain rating scale

    The Numeric pain rating scale is a self-reported, or clinician-administered, measurement tool consisting of a numerical point scale with extreme anchors of no pain to extreme pain. The scale is typically set up on a horizontal or vertical line, ranges most commonly from 0-10 or 0-100, and can be administered in written or verbal form. The 0 on scale shows no pain, 1-4 shows mild pain, 5 and 6 shows moderate pain and 7-10 shows severe pain.

    6 weeks

  • Knee Injury and Osteoarthritis outcome score for Patellofemoral injury

    Knee Injury and Osteoarthritis Outcome Score Patellofemoral is one subjective type of questionnaire developed as an extension with the aim of estimating the immediate and long-term symptoms and function among people with Patellofemoral pain syndrome. Higher scores show pain severity whereas lower score shows mild or no pain.

    6 weeks

  • Single-legged hop tests

    Single-legged hop tests are functional tests that have been used to identify individuals who can regain dynamic knee stability after an ACL injury.

    6 weeks

Study Arms (2)

Isolated Strengthening Exercises

EXPERIMENTAL

Isolated strengthening exercises refers to set of exercises that are used to treat a specific part of body. In our study, isolated strengthening exercises including 10 repetition of 3 sets of legs extensions,10 repetition of 3 sets squats and 10 repetition of 3 sets lunges are used. These exercises aim to improve the pain and range of motion of knee by acting on quadriceps.

Other: Isolated Strengthening Exercises

Combined Strengthening Exercises

EXPERIMENTAL

The Combined strengthening group will perform the same isolated strengthening exercises, but with the addition of proximal strengthening exercises for the hip and core muscles. These exercises include 10 repetitions of bridging(3 sets), 10 repetitions of clamshells(2 sets), 10 repetition of 3 sets of legs extensions,10 repetition of 3 sets squats,10 repetition of 3 sets lunges and 10 repetitions of planks(2 sets).

Other: Isolated Strengthening ExercisesOther: Combined Strengthening Exercises

Interventions

Isolated Strengthening ExercisesOTHER

Isolated strengthening exercises can be beneficial for individuals with Patellofemoral Pain Syndrome (PFPS) to help address muscle imbalances and alleviate pain.

Combined Strengthening ExercisesIsolated Strengthening Exercises
Combined Strengthening ExercisesOTHER

Combined strengthening exercises for Patellofemoral Pain Syndrome (PFPS) typically include a mix of quadriceps strengthening exercises, hip strengthening exercises, and core stability exercises. The goal is to address muscle imbalances and improve the overall stability of the knee joint.

Combined Strengthening Exercises

Eligibility Criteria

Age18 Years - 40 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Professional male basketball players of the age group 18-40 years
  • Practicing players of basketball (3-5 times a week)
  • Players who experience pain around Patella
  • Pain severity between 3 and 10 during stair descending test for PFPS
  • Positive diagnostic patellofemoral syndrome maneuvers including Shrug test, Grind test and Perkins test

You may not qualify if:

  • Past surgery of affected leg
  • Systemic illness (diabetes, systemic lupus erythematosus)
  • Individuals havening significant knee pathologies such as ACL tear, Meniscal tear
  • Referred pain originating from other points of body
  • Knee deformities or signs of knee OA in knee x-ray

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Physio wellness centre

Lahore, Punjab Province, 54782, Pakistan

RECRUITING

Related Publications (2)

  • Mostafaee N, Pashaei-Marandi M, Negahban H, Pirayeh N, Saki Malehi A, Ebrahimzadeh MH. Examining the diagnostic accuracy of common physical examination and functional tests in the diagnosis of patellofemoral pain syndrome among patients with anterior knee pain. Physiother Theory Pract. 2024 Apr;40(4):843-855. doi: 10.1080/09593985.2022.2158053. Epub 2022 Dec 19.

    PMID: 36537113BACKGROUND

  • You S, Shen Y, Liu Q, Cicchella A. Patellofemoral Pain, Q-Angle, and Performance in Female Chinese Collegiate Soccer Players. Medicina (Kaunas). 2023 Mar 16;59(3):589. doi: 10.3390/medicina59030589.

    PMID: 36984590BACKGROUND

MeSH Terms

Conditions

Patellofemoral Pain SyndromePain

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Muhammad Asrar Yousaf, PhD

    Riphah International University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Muhammad Asrar Yousaf, Phd

CONTACT

03004099505asrar.yousaf@riphah.edu.pk

Allah Nawaz, DPT

CONTACT

03337764672allahnawaz909@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 9, 2023

First Posted

November 14, 2023

Study Start

May 5, 2023

Primary Completion

February 5, 2024

Study Completion

February 5, 2024

Last Updated

January 30, 2024

Record last verified: 2024-01

Data Sharing

IPD Sharing
Will not share

Locations

PA(1)