High Intensity Resistance Training With and Without Blood Flow Restriction in ACL Reconstruction

NCT06131047 | Unknown DMC

• 1 other identifier: REC/RCR&AHS/23/0442
• Study Type: interventional
• Target: 26
• Locations: 1 country
• Sites: 1

Brief Summary

This study is randomized and single-blinded. Ethical approval is taken from the ethical committee of riphah international university, Lahore. Participants who meet the inclusion criteria will be enrolled in Groups A \& B through the sealed envelop method by the Non-Probability Convenient random sampling technique. Group A will perform traditional High-intensity resistance training without Blood Flow Restriction training after ACL Reconstruction Surgery. Group B will perform traditional High-intensity Resistance training with Blood Flow Restriction training after ACL Reconstruction Surgery.

Conditions

Resistance Training; Blood Flow Restriction Therapy; Anterior Cruciate Ligament Reconstruction; Volleyball

Keywords

High intensity resistance training; Blood Flow Restriction Traning; ACL reconstruction; Volley ball Players

Outcome Measures

Primary Outcomes (3)

• Strength

  strength will be measured with hand held dynamometer and 1-RM test

  Pre and 6 weeks post interventions

• Agility

  Illinois Agility Test Test will be used to measure agility

  Pre and 6 weeks post interventions

• Power

  Vertical Jump test will be used to measure power

  Pre and 6 weeks post interventions

Study Arms (2)

High Intensity Traditional Resistance Training Group

EXPERIMENTAL

Group A will undergo Traditional Resistance training without blood flow Restriction. A 30-minute progressive, weight training program will be initiated 8 weeks after the ACL-reconstruction and will be conducted subsequent to the individual based program. The resistance (training loads) will be increased when the individual could do more repetitions than the number specified in the weight training protocol. The exercises will be performed at a slow speed to ensure full control of the movement.

Other: High intensity Traditional Resistance Traning without Blood Flow Restriction

High Intensity Traditional Resistance Training with Blood Flow Restriction Group

EXPERIMENTAL

Group B will perform low-load blood flow restriction (LL-BFR) training using external loads of 20-40% 1RM has been suggested as an alternative to traditional strength rehabilitation. Minimum of 2 -3 sets and maximum total 5 sets,20-30 repetitions of each exercise with 30 to 60 seconds rest period and 2-3 times per weekly for 4-6 weeks to During LL-BFR training, a pressurized cuff is applied to the proximal thigh that oc¬cludes venous outflow while maintaining arterial in¬flow. The combination of venous occlusion and resis¬tance training is believed to induce muscle hypertrophy secondary to elevated systematic hormone production, cell swelling, production of reactive oxygen species, intramus¬cular anabolic signaling and fast-twitch fiber recruit¬ment.(

Other: High intensity Traditional Resistance Traning with Blood Flow Restriction

Interventions

High intensity Traditional Resistance Traning without Blood Flow Restriction OTHER

Group A will undergo Traditional Resistance training without blood flow Restriction. A 30-minute progressive, weight training program will be initiated 8 weeks after the ACL-reconstruction and will be conducted subsequent to the individual based program. The resistance (training loads) will be increased when the individual could do more repetitions than the number specified in the weight training protocol. The exercises will be performed at a slow speed to ensure full control of the movement

High Intensity Traditional Resistance Training Group

High intensity Traditional Resistance Traning with Blood Flow Restriction OTHER

Group B will recieve low-load blood flow restriction (LL-BFR) training using external loads of 20-40% 1RM has been suggested as an alternative to traditional strength rehabilitation. Minimum of 2 -3 sets and maximum total 5 sets,20-30 repetitions of each exercise with 30 to 60 seconds rest period and 2-3 times per weekly for 4-6 weeks to During LL-BFR training, a pressurized cuff is applied to the proximal thigh that oc¬cludes venous outflow while maintaining arterial in¬flow. The combination of venous occlusion and resis¬tance training is believed to induce muscle hypertrophy secondary to elevated systematic hormone production, cell swelling, production of reactive oxygen species, intramus¬cular anabolic signaling and fast-twitch fiber recruit¬ment

High Intensity Traditional Resistance Training with Blood Flow Restriction Group

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Male players with age group 18 to 25 years,Return to function phase of rehabilitation,Players with Grade III ACL Tear ,Athletes who have been playing for at least 2 years

You may not qualify if:

• Players after ACL Reconstruction in acute or subacute phase,Players with other biomechanical issues of knee or feet,Players with any hematological disorders or hypertension

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Ghurki Trust & Teaching Hospital

Lahore, Punjab Province, 543000, Pakistan

RECRUITING

Related Publications (6)

• Moses B, Orchard J, Orchard J. Systematic review: Annual incidence of ACL injury and surgery in various populations. Res Sports Med. 2012 Jul;20(3-4):157-79. doi: 10.1080/15438627.2012.680633.

  PMID: 22742074 BACKGROUND

• Kruse LM, Gray B, Wright RW. Rehabilitation after anterior cruciate ligament reconstruction: a systematic review. J Bone Joint Surg Am. 2012 Oct 3;94(19):1737-48. doi: 10.2106/JBJS.K.01246.

  PMID: 23032584 BACKGROUND

• Elabd OM, Elabd AM. Functional outcomes of a criterion-based rehabilitation protocol for anterior cruciate ligament reconstruction in amateur athletes: A randomised clinical trial. J Bodyw Mov Ther. 2023 Jul;35:7-13. doi: 10.1016/j.jbmt.2023.04.037. Epub 2023 Apr 17.

  PMID: 37330806 BACKGROUND

• Kirby JC, Whitehead TS, Webster KE, Feller JA, McClelland JA, Klemm HJ, Devitt BM. Impact of Occupation on 12-Month Outcomes After Anterior Cruciate Ligament Reconstruction in Male Patients. Orthop J Sports Med. 2023 Feb 22;11(2):23259671221130377. doi: 10.1177/23259671221130377. eCollection 2023 Feb.

  PMID: 36846817 BACKGROUND

• Lorenz DS, Bailey L, Wilk KE, Mangine RE, Head P, Grindstaff TL, Morrison S. Blood Flow Restriction Training. J Athl Train. 2021 Sep 1;56(9):937-944. doi: 10.4085/418-20.

  PMID: 34530434 BACKGROUND

• Koc BB, Truyens A, Heymans MJLF, Jansen EJP, Schotanus MGM. Effect of Low-Load Blood Flow Restriction Training After Anterior Cruciate Ligament Reconstruction: A Systematic Review. Int J Sports Phys Ther. 2022 Apr 1;17(3):334-346. doi: 10.26603/001c.33151. eCollection 2022.

  PMID: 35391871 BACKGROUND

Study Officials

• Muhammad Nouman Tabassum, DPT

  Ghurki Trust & Teaching Hospital,Lahore

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Muhammad Atif Javed, PP-DPT

CONTACT

+92-3317491071; atif.javed@riphah.edu.pk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: Asessor who will take readings is blind
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Randomized Clinical trial

Study Record Dates

• First Submitted: November 9, 2023
• First Posted: November 14, 2023
• Study Start: October 20, 2023
• Primary Completion: February 20, 2024
• Study Completion: February 20, 2024
• Last Updated: November 14, 2023

Record last verified: 2023-11

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)