NCT06106373

Brief Summary

Prospective, non-randomized, open-label study to evaluate the safety and efficacy of the iotaSOFT Insertion System when used to assist electrode array insertion during cochlear implant surgery in a pediatric population.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2022

Typical duration for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 17, 2022

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

October 24, 2023

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 30, 2023

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 24, 2024

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 10, 2025

Completed
Last Updated

September 15, 2025

Status Verified

September 1, 2025

Enrollment Period

2.4 years

First QC Date

October 24, 2023

Last Update Submit

September 9, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Safety related to adverse events

    Evaluation of iotaSOFT related adverse events and serious adverse events through 30 days after surgery

    30 days following surgery

Study Arms (1)

Pediatric Cochlear Implant Recipient

EXPERIMENTAL

Pediatric subjects receiving a cochlear implant between the ages of 9 months and under 12 years of age.

Device: iotaSOFT Insertion System

Interventions

robotic assistive technology for cochlear implant electrode insertion

Pediatric Cochlear Implant Recipient

Eligibility Criteria

Age9 Months - 12 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Candidate for unilateral or bilateral cochlear implantation according to indications for use with FDA approved cochlear implant devices
  • Age 9 months to less than 12 years old at the time of CI surgery
  • Willingness to participate in the study and able to comply with the follow-up visit requirements

You may not qualify if:

  • Prior cochlear implantation in the ear to be implanted
  • Ossification or any other cochlear anomaly that might prevent complete insertion of the electrode array or present an increased risk of aberrant insertion
  • Craniofacial abnormality, temporal squamosal skull thickness less than 3mm, major cochlear lesions, or cochlear malformations
  • Deafness due to lesions of the acoustic nerve or central auditory pathway
  • Diagnosis of auditory neuropathy.
  • Active middle-ear infection or tympanic membrane perforation in the presence of active middle-ear disease
  • Absence of cochlear development
  • Additional medical concerns that would prevent participation in evaluations as determined by the investigator
  • Planned or current participation in a clinical study of an investigational device or drug

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

University of Iowa

Iowa City, Iowa, 52242, United States

Location

Texas Childrens Hospital

Houston, Texas, 77030, United States

Location

MeSH Terms

Conditions

Hearing Loss, SensorineuralHearing Loss, BilateralHearing Loss, Unilateral

Condition Hierarchy (Ancestors)

Hearing LossHearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Laura Chenier

    iotaMotion, Inc.

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 24, 2023

First Posted

October 30, 2023

Study Start

May 17, 2022

Primary Completion

October 24, 2024

Study Completion

July 10, 2025

Last Updated

September 15, 2025

Record last verified: 2025-09

Locations