NCT06105970

Brief Summary

By validating Hierarchy Model of psychopathology(HiTOP) in Chinese community samples, this study aims for illumating the problem of diagnostic heterogeneity and high comorbidity within existing psychiatric classification systems in Chinese culture. Concurrently, this study also focuses on exploring trans-diagonostic risk and proctective factors underline HiTOP dimensions. the main questions it aims to answer are:

  1. 1.Explore HiTOP model cultural differences between western culture and eastern culture.
  2. 2.Understand the impact of different dimension of adverse childhood experience on HiTOP structure.
  3. 3.Investigate the relationship between individual unique psychological variables and psychopathological dimensions.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,000

participants targeted

Target at P75+ for all trials

Timeline
18mo left

Started Sep 2023

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress64%
Sep 2023Nov 2027

Study Start

First participant enrolled

September 26, 2023

Completed
28 days until next milestone

First Submitted

Initial submission to the registry

October 24, 2023

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 30, 2023

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2024

Completed
3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2027

Expected
Last Updated

July 10, 2025

Status Verified

July 1, 2025

Enrollment Period

1.1 years

First QC Date

October 24, 2023

Last Update Submit

July 5, 2025

Conditions

Keywords

Hierarchical Model of Psychopathology

Outcome Measures

Primary Outcomes (2)

  • Chinese version of Hierarchy Model of psychopathology

    Constructing the Chinese version of Hierarchy Model of psychopathology. Comparing the differences between Chinese version and western version.

    1 year

  • Mapping different dimension of adverse childhood experience on Hierarchy Model of psychopathology structure

    1 year

Secondary Outcomes (1)

  • Investigate the relationship between individual unique psychological variables and psychopathological dimensions.

    4 years

Study Arms (1)

Community sample

Using social media to randomly inviting participants across all regions of China.

Other: No intervention

Interventions

cross sectional study#no intervention

Community sample

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

This study aims to recruits partcipants across the whole regions of China, with the aim of collecting representative Chinese community sample.

You may qualify if:

  • Chinese citizens
  • Years of education \> =9 years.
  • age \>= 18 years old.

You may not qualify if:

  • (1)Subjects who have insufficient self-awareness, and are unable to obtain complete informed consent, such as: schizophrenia, manic episode of bipolar disorder, severe depression.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shanghai Mental Health Center

Shanghai, China

RECRUITING

Study Officials

  • Zhen Wang, PhD, MD

    Shanghai Mental Health Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Zhen Wang, Phd, MD

CONTACT

Study Design

Study Type
observational
Observational Model
ECOLOGIC OR COMMUNITY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
vice-president

Study Record Dates

First Submitted

October 24, 2023

First Posted

October 30, 2023

Study Start

September 26, 2023

Primary Completion

November 1, 2024

Study Completion (Estimated)

November 1, 2027

Last Updated

July 10, 2025

Record last verified: 2025-07

Locations