Fat Grafting an Ideal Filler For Contour Deformities With Hyperpigmentation On Face

NCT06103461 | Completed DMC

• 1 other identifier: kemu/23/1
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Pigmentary changes are commonly associated with contour defects of facial region. These deformities cause cosmetic concerns. Traditionally used techniques indwelling limitations and therefore it invokes innovative techniques to treat contour abrasion and pigmentation simultaneously. The current study focuses on evaluation of the role of autologous fat in improving contour defects of face associated with hyperpigmentation. 100 subjects having contour defects related skin pigmentation were recruited from Feb 2022 till Feb 2023. Fat was harvested, processed under sterilized conditions and grafted into the affected regions of face. The patients were kept under follow up for one year after fat injection. Subjective as well as objective evaluation was done before treatment and one year after fat injection. Results showed significant improvement in pigmentation after fat injection. Most of the patients had high satisfaction regarding improvement in pigmentation and pliability of the grafted area after use of fat graft. A software Image J was applied to objectively showing changes in hyperpigmentation of face after fat graft. In conclusion, utility of autologous fat has effective and promising role as an ideal filler for treating contour defects of face with pigmentary changes

Conditions

Hyperpigmentation

Keywords

Pigmentation; Contour defect; Fat grafting

Outcome Measures

Primary Outcomes (1)

• IDC

  integrated color density

  6 Months

Study Arms (1)

Fat Grafting

EXPERIMENTAL

It is an experimental study for effect of fat grafting on pigmentation of skin

Procedure: Autologous fat grafting

Interventions

Autologous fat grafting PROCEDURE

Autologous fat grafted at contour defects with pigmentary changes

Fat Grafting

Eligibility Criteria

• Age: 10 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Pigmentation with contour defect

You may not qualify if:

• Unfit for anesthesia

Sponsors & Collaborators

• King Edward Medical University: lead

Study Sites (1)

King Edward Medical University

Lahore, Punjab Province, 54000, Pakistan

Location

MeSH Terms

Conditions

Hyperpigmentation

Condition Hierarchy (Ancestors)

Pigmentation Disorders; Skin Diseases; Skin and Connective Tissue Diseases

Study Officials

• Afzaal Bashir, FACS, MS

  King Edward Medical University, Lahore, Pakistan

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Model Details: Cohort study

Study Record Dates

• First Submitted: October 21, 2023
• First Posted: October 26, 2023
• Study Start: February 22, 2022
• Primary Completion: February 21, 2023
• Study Completion: February 21, 2023
• Last Updated: October 26, 2023

Record last verified: 2023-10

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)