NCT06031116

Brief Summary

the investigator compares the clinical outcomes and pain levels after gingival depigmentation by ceramic soft tissue bur vs scalpel surgery

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
8

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 10, 2022

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

December 19, 2022

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 10, 2023

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

May 10, 2023

Completed
4 months until next milestone

First Posted

Study publicly available on registry

September 11, 2023

Completed
Last Updated

September 11, 2023

Status Verified

September 1, 2023

Enrollment Period

6 months

First QC Date

December 19, 2022

Last Update Submit

September 8, 2023

Conditions

Outcome Measures

Primary Outcomes (3)

  • clinical outcomes of depigmentation procedure

    dummet oral pigmentation index ( DOPI): 1= pink no pigmentation (better) 4= deep brown (worse) Melanin index (MI):1= isolated pigment (better), 4= long continous ribbon (worse). reported by visual inspection.

    3 month postoperative

  • patient satisfaction

    global aesthetic improvement scale 5 point likert scale 1= excellent improvement 5= worsened. patient reported outcome. a score from 1 to 5, 1 being better

    3 months postoperative

  • Percieved pain

    postoperative pain will be assessed using visual analoque scale (VAS): 1= being the least pain and 10= being the most severe

    7 days

Secondary Outcomes (2)

  • operating time

    during surgery

  • Wound healing

    7 days postoperative

Study Arms (2)

ceramic soft tissue bur

EXPERIMENTAL

Eight dental arches were treated by ceramic soft tissue bur

Procedure: depigmentation

scalpel

ACTIVE COMPARATOR

Eight dental arches were treated by conventional scalpel technique

Procedure: depigmentation

Interventions

gingival depigmentation

ceramic soft tissue burscalpel

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Males and females within age range of 20-50 years.
  • Systemic (medically) free individuals.
  • Gingival pigmentation score \> 3 on Hedin melanin index15.
  • Patients with good oral hygiene.
  • Patients with thick gingival phenotype.

You may not qualify if:

  • Smokers.
  • Teeth with compromised periodontium.
  • Pregnant and lactating females.
  • The vulnerable group: patients with mental or physical disabilities.
  • Medications that cause gingival pigmentation.
  • Pathologies that cause gingival pigmentation.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ainshams university

Cairo, Cairo Governorate, 11671, Egypt

Location

MeSH Terms

Conditions

Hyperpigmentation

Condition Hierarchy (Ancestors)

Pigmentation DisordersSkin DiseasesSkin and Connective Tissue Diseases

Study Officials

  • Yasmine El sayed, Phd

    Ain Shams University

    STUDY DIRECTOR
  • Hala Abu elela, Phd

    Ain Shams University

    STUDY CHAIR
  • Sally Nassar, Bds

    Ain Shams University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: split mouth (dental arches)
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dentist

Study Record Dates

First Submitted

December 19, 2022

First Posted

September 11, 2023

Study Start

October 10, 2022

Primary Completion

April 10, 2023

Study Completion

May 10, 2023

Last Updated

September 11, 2023

Record last verified: 2023-09

Locations