Assessment of Epicardial Fat Thickness in Children With Familial Dyslipidemia
1 other identifier
observational
42
0 countries
N/A
Brief Summary
Aim of the study: 1- Detect common types of familial dyslipidemia. 2- Significance and relationship between Epicardial fat thickness and familial dyslipidemia.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Dec 2023
Typical duration for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 19, 2023
CompletedFirst Posted
Study publicly available on registry
October 26, 2023
CompletedStudy Start
First participant enrolled
December 20, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 20, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
December 30, 2025
CompletedOctober 26, 2023
October 1, 2023
2 years
September 19, 2023
October 22, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
assessment epicardial fat thickness in children with familial dyslipidemia
All cases included in the study will be evaluated by: 1. \- Fasting lipid profile: Total cholesterol, High-density lipoprotein (HDL) cholesterol, Low-density lipoprotein (LDL) cholesterol, Triglycerides (TG). (18) 2. \- Transthoracic Echocardiography.
baseline
Study Arms (1)
dyslipidemia
Normal weight children more than 1 month and till age of 18 years that attend Assiut University children Hospital with Clinical manifestation: 1. Non-symptomatic accidentally discovered dyslipidemia. 2. Steatorrhea. 3. Fatty liver.
Interventions
Assessment of epicardial fat thickness in children with familial dyslipidemia
Eligibility Criteria
Setting: Tertiary care center ( Assiut University children Hospital) (AUCH) from Sep 2023 to Sep 2025. Normal weight children more than 1 month and till age of 18 years that attend Assiut University children Hospital with Clinical manifestation: 1. Non-symptomatic accidentally discovered dyslipidemia. 2. Steatorrhea. 3. Fatty liver.
You may qualify if:
- Normal weight children more than 1 month and till age of 18 years that attend Assiut University children Hospital with Clinical manifestation:
- Non-symptomatic accidentally discovered dyslipidemia.
- Steatorrhea.
- Fatty liver
You may not qualify if:
- Patients who had poor echo window : chest deformities, chronic lung disease, pericardial and/or pleural effusion on transthoracic echocardiography, and chronic kidney disease were not included in the study.
- \. Congenital heart diseases. 3. Children with liver diseases that cause 2ry dyslipidemia. 4. Children with Diabetes that cause 2ry dyslipidemia
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Amr Mohamed Kotb, Lecturer of Pediatrics
Assiut University
- STUDY DIRECTOR
Mohamed Abou Bakr Sobeih, Lecturer of Pediatrics
Assiut University
Central Study Contacts
Faisal-Al Khateeb Al Khateeb ahmed, professor of pediatrics
CONTACT
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Resident doctor of Pediatrics, Faculty of Medicine, Assiut University, Principal Investigator.
Study Record Dates
First Submitted
September 19, 2023
First Posted
October 26, 2023
Study Start
December 20, 2023
Primary Completion
December 20, 2025
Study Completion
December 30, 2025
Last Updated
October 26, 2023
Record last verified: 2023-10