Comparison of Midpoint Transverse Process to Pleura Block and Thoracic Paravertebral Block

NCT06089512 | Completed

• 1 other identifier: 2022-17/22
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, hypothesis is that the MTPB (mid point transverse process block), which is easier and has fewer complications in patients aged 18-80 undergoing video-assisted thoracic surgery (VATS), provides analgesia as effective as PVB.

Conditions

Analgesia; Post Operative Pain

Keywords

thoracic; analgesia; post operative pain; surgery-complication

Outcome Measures

Primary Outcomes (2)

• Intraoperative analgesic effects of peripheral blocks

  Investigators will compare the intraoperative analgesic effects by opioid consumption in intraoperative phase.

  First day

• Postoperative analgesic effects of peripheral blocks

  Visual Analogue Scale (VAS) will be used for postoperative analgesic effects.

  First day

Secondary Outcomes (2)

• opioid consumed through PCA (patient controlled analgesia)

  first day

• Side effects

  First day

Study Arms (3)

Control group

PLACEBO COMPARATOR

group receiving general anesthesia only

Procedure: Control group

paravertebral block group

ACTIVE COMPARATOR

received single-shot paravertebral block after induction of anesthesia.

Procedure: paravertebral block group

mid transverse process block group

ACTIVE COMPARATOR

received a mid-transverse process -to- pleura block after induction of anesthesia.

Procedure: Mid point transverse process block group

Interventions

paravertebral block group PROCEDURE

Paravertebral block was applied to the patients after induction of general anesthesia; Intraoperative opioid requirement and postoperative pain scores and analgesic requirement were evaluated.

paravertebral block group

Mid point transverse process block group PROCEDURE

Mid point transverse process block was applied to the patients after induction of general anesthesia; Intraoperative opioid requirement and postoperative pain scores and analgesic requirement were evaluated.

mid transverse process block group

Control group PROCEDURE

Only general anesthesia was applied to the patients.

Control group

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients between 18 and 80 years of age
• American Society of Anesthesiologists I-II physical status of and
• Body mass index of 19 to 28 kg/m2

You may not qualify if:

• Patients who had coagulopathy
• Previous thoracic surgery
• Emotional instability
• Significant encephalopathy
• Preexisting motor or sensory deficit
• Other contraindications to local anaesthesia, such as allergies

Sponsors & Collaborators

• Uludag University: lead

Study Sites (1)

Bursa Uludag University

Bursa, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Agnosia; Pain, Postoperative

Interventions

Control Groups

Condition Hierarchy (Ancestors)

Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Postoperative Complications; Pathologic Processes; Pain

Intervention Hierarchy (Ancestors)

Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Study Officials

• seda cansabuncu

  BURSA ULUDAG UNIVERSITY HOSPITAL

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: September 29, 2023
• First Posted: October 18, 2023
• Study Start: November 1, 2022
• Primary Completion: August 15, 2023
• Study Completion: August 20, 2023
• Last Updated: October 18, 2023

Record last verified: 2023-10

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)