NCT03416075

Brief Summary

To identify risk factors for mortality in patients with interstitial lung disease receiving mechanical ventilation.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
94

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2011

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2011

Completed
7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2017

Completed
7 days until next milestone

First Submitted

Initial submission to the registry

January 7, 2018

Completed
23 days until next milestone

First Posted

Study publicly available on registry

January 30, 2018

Completed
Last Updated

January 30, 2018

Status Verified

January 1, 2018

Enrollment Period

7 years

First QC Date

January 7, 2018

Last Update Submit

January 29, 2018

Conditions

Interstitial Lung DiseaseMechanical VentilationRisk FactorsMorality

Outcome Measures

Primary Outcomes (1)

  • ICU Mortality

    7 years

Secondary Outcomes (3)

  • Hospital mortality

    7 years

  • Noninvasive mechanical ventilation failure

    7 years

  • Invasive mechanical ventilation failure

    7 years

Interventions

Mechanical ventilationDEVICE

Noninvasive and/or invasive mechanical ventilation were performed when patients had respiratory failure.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients were diagnosed as interstitial lung disease and received mechanical ventilation.

You may qualify if:

  • They were clearly diagnosed as interstitial lung disease in hospital;
  • They had progressive worsening of dyspnea and their oxygenation indexes were less than 300 in ICU;
  • They received at least 48 hours of mechanical ventilation after being admitted into ICU.

You may not qualify if:

  • We excluded patients who were admitted into ICU because of postoperative monitoring.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Lung Diseases, Interstitial

Interventions

Respiration, Artificial

Condition Hierarchy (Ancestors)

Lung DiseasesRespiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Airway ManagementTherapeuticsResuscitationEmergency TreatmentRespiratory Therapy

Study Officials

  • Zujin Luo, MD

    Beijing Chao Yang Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Attending physician

Study Record Dates

First Submitted

January 7, 2018

First Posted

January 30, 2018

Study Start

January 1, 2011

Primary Completion

December 31, 2017

Study Completion

December 31, 2017

Last Updated

January 30, 2018

Record last verified: 2018-01

Data Sharing

IPD Sharing
Will not share