A Prognostic Model Based on POCUS at ICU Admission in Critically Ill Patients With Sepsis

NCT06082154 | Completed DMC

• 1 other identifier: 506(6-11)E2
• Study Type: observational
• Target: 175
• Locations: 1 country
• Sites: 1

Brief Summary

Sepsis is responsible for one in three patient deaths. Understanding the severity of the disease, directing medications, prognosticating, and communicating with family members depend on the ability to predict outcomes in a patient presenting with sepsis in the ICU. The outcome of mortality reflects the caliber of ICU treatment. This is a prospective observational study that will include all patients diagnosed with sepsis for point-of-care ultrasonography within 24 hours of admission to the ICU from April 26, 2023, to March 30, 2024, and create a model that will predict 28 day outcome in these patients.

Conditions

Sepsis

Outcome Measures

Primary Outcomes (1)

• 28 day status alive or dead

  patient will be followed for 28 days from day of icu admission to find out their status being alive or dead

  28 days

Interventions

ultrasound DEVICE

Patient will undergo multiorgan ultrasonography

Eligibility Criteria

• Age: 16 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patient who are diagnosed as having sepsis as per Sepsis 3 definition

You may qualify if:

• Age \>=16 yrs within 24 hour of ICU admission diagnosed as Sepsis as per Sepsis 3

You may not qualify if:

• USG cannot be done within 24 hour of admission to icu If USG cannot be done for 2 parameters Who do not give consent Withdrawal of active life support Do not intubate(DNI) or do not resuscitate(DNR) order at admission

Sponsors & Collaborators

• Tribhuvan University Teaching Hospital, Institute Of Medicine.: lead

Study Sites (1)

Ashmita Paudel

Kathmandu, Bagmati, 1524, Nepal

Location

MeSH Terms

Conditions

Sepsis

Interventions

Ultrasonography

Condition Hierarchy (Ancestors)

Infections; Systemic Inflammatory Response Syndrome; Inflammation; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: October 7, 2023
• First Posted: October 13, 2023
• Study Start: April 26, 2023
• Primary Completion: April 30, 2024
• Study Completion: April 30, 2024
• Last Updated: August 2, 2024

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will not share

Locations

NE (1)