Improving Pancreatic Cancer Care by the Use of Computational Science and Technology

NCT06055010 | Recruiting DMC

• 1 other identifier: 212191910
• Study Type: observational
• Target: 5,000
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of the IMPACT project is to set up a data sharing infrastructure between expert centers for pancreatic surgery that enables training, testing and validation of computer science tools to improve quality of care for patients with pancreatic cancer.

Conditions

Pancreatic Cancer; Pancreatic Cyst; Pancreatic Adenocarcinoma; Pancreatic Diseases; Pancreas Adenocarcinoma; Pancreas Cyst

Keywords

Artificial Intelligence; Data Science; Computer Science; Pancreatic Cancer

Outcome Measures

Primary Outcomes (1)

• Subproject dependent

  Endpoints within this project are dependent on the specific subprojects. This study will facilitate the collection of large amounts of real-world data for (future) computer science projects.

  Through study completion, an average of 5 years.

Study Arms (2)

Healthy individuals

Healthy individuals who received an abdominal CT-scan (controls).

Other: No interventions

Individuals with pancreatic lesions

Patients who received diagnostic procedures and/or treatment for (suspected) benign and malignant pancreatic lesions as registered in the Dutch Pancreatic Cancer Project (PACAP) audit database

Other: No interventions

Interventions

No interventions OTHER

Considering the retrospective nature of this project and use of existing clinical and technical data, this project contains no interventions or prospective inclusion of healthy subjects / patients for the execution of experiments.

Healthy individuals; Individuals with pancreatic lesions

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients who underwent diagnostic procedures and/or treatment for (suspected) benign and malignant pancreatic lesions as registered in the Dutch Pancreatic Cancer Project (PACAP) audit database, as well as healthy individuals who received an abdominal CT-scan (controls).

You may qualify if:

• ≥18 years of age
• Patients who received diagnostic procedures and/or treatment for (suspected) benign and malignant pancreatic lesions as registered in the Dutch Pancreatic Cancer Project (PACAP) audit database and healthy individuals who received an abdominal CT-scan (controls)

You may not qualify if:

• \- Subjects who object to the use of their data for the purpose of scientific research

Sponsors & Collaborators

• UMC Utrecht: lead
• Catharina Ziekenhuis Eindhoven: collaborator
• St. Antonius Hospital: collaborator
• Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA): collaborator
• University Medical Center Groningen: collaborator
• Medisch Spectrum Twente: collaborator
• Erasmus Medical Center: collaborator
• Maastricht University Medical Center: collaborator
• Leiden University Medical Center: collaborator
• NYU Langone Health: collaborator
• Johns Hopkins University: collaborator
• Delft University of Technology: collaborator

Study Sites (1)

Regional Academic Cancer Center Utrecht

Utrecht, 3584 CX, Netherlands

RECRUITING

MeSH Terms

Conditions

Pancreatic Neoplasms; Pancreatic Cyst; Pancreatic Diseases

Condition Hierarchy (Ancestors)

Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Endocrine Gland Neoplasms; Digestive System Diseases; Endocrine System Diseases; Cysts

Central Study Contacts

Lois A Daamen, MD, PhD

CONTACT

+31651223276; l.a.daamen-3@umcutrecht.nl

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 30, 2023
• First Posted: September 26, 2023
• Study Start: January 1, 2014
• Primary Completion (Estimated): December 31, 2029
• Study Completion (Estimated): December 31, 2029
• Last Updated: September 26, 2023

Record last verified: 2023-09

Locations

NL (1)