NCT02079428

Brief Summary

The purpose of CN-HF is to establish the national registration of hospitalized heart failure patients, evaluate and compare the clinical features and prognosis of diastolic and systolic heart failure, and find out the status of treatment and implementation of guidelines on heart failure in China.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
10,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2013

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2013

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

March 2, 2014

Completed
3 days until next milestone

First Posted

Study publicly available on registry

March 5, 2014

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2016

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2016

Completed
Last Updated

March 5, 2014

Status Verified

March 1, 2014

Enrollment Period

3.4 years

First QC Date

March 2, 2014

Last Update Submit

March 4, 2014

Conditions

Cardiac FailureCongestive Heart Failure

Keywords

Heart FailureRegistryChina

Outcome Measures

Primary Outcomes (1)

  • Number of death

    36 months after index discharge

Secondary Outcomes (1)

  • Number of patients rehospitalized for worsened heart failure

    36 months after index discharge

Other Outcomes (1)

  • Change from baseline in New York Heart Association (NYHA) cardiac function classes

    36 months after index discharge

Study Arms (1)

Systolic heart failure, Diastolic heart failure

Other: No interventions

Interventions

No interventionsOTHER
Systolic heart failure, Diastolic heart failure

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The study planed to consecutively enroll 10 000 heart failure patients fulfilling the inclusion criteria. Each center will register all patients with heart failure involved in the discharge or death diagnosis in consecutive 6 months.

You may qualify if:

  • Patients discharged from the department of cardiology;
  • Discharge or death diagnosis involves diseases with I50 as the beginning of the International Classification of Diseases (ICD)-10 code, including congestive heart failure, congestive heart disease, cardiac failure, right side heart failure, right side ventricular failure, acute left side heart failure, chronic left side cardiac dysfunction, cardiac asthma, left side heart failure, left side heart failure with acute pulmonary edema, low cardiac output syndrome, cardiac dysfunction, acute heart failure, chronic heart failure, grade Ⅱ cardiac function class, grade Ⅲ cardiac function class, grade Ⅱ-Ⅲ cardiac function class, grade Ⅳ cardiac function class, heart failure, cardiac-renal failure, circulatory failure, and grade Ⅰcardiac function class (I51.903), pregnancy with heart failure (O99.408), pregnancy with cardiac dysfunction (O99.429), postpartum cardiac dysfunction (O99.434), post-operative heart failure with pulmonary edema (I97.104), and heart failure after cardiac surgery (I97.106);
  • Agree to sign an informed consent form.

You may not qualify if:

  • Refuse to sign an informed consent form;
  • Already involved in this study during previous hospitalization.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University

Shanghai, 200032, China

RECRUITING

Related Publications (2)

  • Zhou J, Cao J, Jin X, Zhou J, Chen Z, Xu D, Yang X, Dong W, Li L, Fan Y, Chen L, Zhong Q, Fu M, Hu K, Ge J; CN-HF investigators. Digoxin is associated with worse outcomes in patients with heart failure with reduced ejection fraction. ESC Heart Fail. 2020 Feb;7(1):138-146. doi: 10.1002/ehf2.12539. Epub 2020 Jan 29.

    PMID: 31994361DERIVED

  • Jin X, Cao J, Zhou J, Wang Y, Han X, Song Y, Fan Y, Chen Z, Xu D, Yang X, Dong W, Li L, Chen L, Zhong Q, Fu M, Hu K, Zhou J, Ge J; CN-HF investigators. Outcomes of patients with anemia and renal dysfunction in hospitalized heart failure with preserved ejection fraction (from the CN-HF registry). Int J Cardiol Heart Vasc. 2019 Aug 31;25:100415. doi: 10.1016/j.ijcha.2019.100415. eCollection 2019 Dec.

    PMID: 31508483DERIVED

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Officials

  • Jingmin Zhou, Professor

    Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Jingmin Zhou, Professor

CONTACT

86 13601954136zhou.jingmin@zs-hospital.sh.cn

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
3 Years
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 2, 2014

First Posted

March 5, 2014

Study Start

January 1, 2013

Primary Completion

June 1, 2016

Study Completion

December 1, 2016

Last Updated

March 5, 2014

Record last verified: 2014-03

Locations

CN(1)