Outcome Evaluation After Fertility Preservation

NCT06043609 | Recruiting

• 1 other identifier: 2023.346
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

It is important to evaluate outcomes after different fertility preservation strategies. Therefore, this study aims to assess the outcomes after different fertility preservation strategies and identify any factors that may affect their reproductive outcome.

Conditions

Cancer; Fertility Issues

Outcome Measures

Primary Outcomes (1)

• To determine any factors that may affect the success rate of different fertility preservation methods.

  The medical notes of these patients undergoing fertility preservation services will be reviewed. The baseline characteristics including the socio-demographic background will be obtained by reviewing their hospital record.

  10 years

Secondary Outcomes (2)

• To assess the pregnancy rate after different fertility preservation methods.

  10 years

• To report on the frequency of surgical complications

  10 years

Interventions

This is an observational cohort study OTHER

This is an observational cohort study

Eligibility Criteria

• Age: Up to 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

All patients who have undergone or will seek for fertility preservation services in PWH will be invited to participate.

You may qualify if:

• Patients aged from 0-50 years old
• Patients with any illness or who will undergo any type of treatment that may cause irreversible damage to their fertility, such as extensive abdominal surgery, high toxicity medication and treatments;
• Patients seek for fertility preservation services

You may not qualify if:

• Patients unable to provide consent/assent (i.e. significant psychiatric problems/cognitive delay)

Sponsors & Collaborators

• Chinese University of Hong Kong: lead

Study Sites (1)

Prince of Wales Hospital

Hong Kong, Hong Kong

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

When patients come back after the use of frozen gametes, embryos or tissue, discarded or residual cryopreserved gamete, embryos or tissue will be used for histological and pathological assessment to determine its quality. Donated samples cannot be retrieved/ used for future fertility treatment.

MeSH Terms

Conditions

Neoplasms; Infertility

Condition Hierarchy (Ancestors)

Genital Diseases; Urogenital Diseases

Study Officials

• Jacqueline CHUNG, MBBS

  Chinese University of Hong Kong

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Jacqueline CHUNG, MBBS

CONTACT

35051537; jacquelinechung@cuhk.edu.hk

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: September 12, 2023
• First Posted: September 21, 2023
• Study Start: September 21, 2023
• Primary Completion (Estimated): October 1, 2033
• Study Completion (Estimated): October 1, 2035
• Last Updated: January 8, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

HK (1)