NCT07052110

Brief Summary

This study aims to examine the effectiveness of Digital storytelling (DST) in reducing depressive symptoms, enhancing self-esteem, and promoting quality of life among Chinese survivors of childhood cancer. Participants in the experimental group will be divided into groups of 6 to 8 childhood cancer survivors to receive the intervention, which comprises four workshops. Each workshop will last 2.5 hours and will be conducted by a qualified interventionist. Parents are not required to attend the workshop. The investigators will provide a waiting room for them. Parents will also be provided with a leaflet developed by Hong Kong Department of Health which contains self-help material for depression. No intervention will be carried out among participants in the control group. However, customary care including medical follow-up, medication prescription, and nursing interventions will be provided, as usual. Parents will also be provided with a leaflet containing self-help materials for depression.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
248

participants targeted

Target at P75+ for not_applicable cancer

Timeline
4mo left

Started Oct 2023

Typical duration for not_applicable cancer

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress88%
Oct 2023Sep 2026

Study Start

First participant enrolled

October 16, 2023

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

June 26, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

July 4, 2025

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 12, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 12, 2026

Last Updated

March 12, 2026

Status Verified

March 1, 2026

Enrollment Period

2.9 years

First QC Date

June 26, 2025

Last Update Submit

March 10, 2026

Conditions

Keywords

childhood cancer survivorsdigitial storytellingdepressive symptomsself-esteemquality of life

Outcome Measures

Primary Outcomes (1)

  • Depressive symptoms: Chinese version of the Center for Epidemiological Studies Depression Scale for Children (CES-DC)

    The CES-DC will be used to assess the number of depressive symptoms among participants. This instrument contains 20 items evaluated on a 4-point scale, from 0 (not at all) to 3 (a lot). The possible range of scores is between 0 and 60, with higher scores indicating more depressive symptoms. The cut-off score is 15. Participants with scores higher than 15 are considered to be experiencing significant levels of depressive symptoms. This scale has been widely applied in studies among Hong Kong Chinese children with cancer, and its psychometric properties have been well-established in this population.

    The CES-DC will be conducted immediately after the completion of the intervention, and at 1-, 3- and 6-month follow-up via telephone interview.

Secondary Outcomes (2)

  • Self-esteem: Chinese version of the Rosenberg Self-Esteem Scale (RSES)

    The RSES will be conducted immediately after the completion of the intervention, and at 1-, 3- and 6-month follow-up via telephone interview.

  • Quality of life: Chinese version of the Pediatric Quality of Life Inventory 4.0 Generic Core Scale (PedsQL 4.0)

    The PedsQL 4.0 will be conducted immediately after the completion of the intervention, and at 1-, 3- and 6-month follow-up via telephone interview.

Study Arms (2)

Intervention: Digital storytelling

EXPERIMENTAL

Participants in the experimental group will receive the DST intervention, which comprises four workshops. Each workshop will last 2.5 hours and will be conducted by a qualified interventionist. In the workshops, a group of 6-8 participants will first share their personal cancer experiences and offer feedback to other participants in the context of a story circle. A set of guiding questions will be used to facilitate participants in telling their own stories. Particularly, probing will be used to guide the child participants to share their own experiences. Open-ended questions such as 'How do you think about your cancer experience?' will be asked. Subsequent supplementary questions, such as 'What makes you feel in this way?' and 'can you give me some examples' will be asked to encourage more sharing. Afterwards, participants wil be encouraged to write their own script and storyboard, record their stories using a microphone, and choose photos and videos to illustrate their stories.

Other: Digital storytelling

No Intervention: Standard of care

NO INTERVENTION

No intervention will be carried out among participants in the control group. However, customary care including medical follow-up, medication prescription, and nursing interventions will be provided, as usual.

Interventions

DST is an intervention that can potentially mitigate the psychological impact of traumatic experiences. People can usually find positive meaning in a traumatic experience by communicating their experience using narratives like storytelling. In particular, by externalising the traumatic experience in the form of a narrative, the individual can become an objective agent, distancing themselves from negative meanings attached to the experience. This lowers people's resistance to and defence against the experience, assisting them to explore alternative perspectives regarding the experience and to identify its positive aspects, which boost self-esteem. Likewise, storytelling engages different areas of the brain, including those responsible for visual, language, and hearing functions, to reorganise the disorganised traumatic experience into a coherent story, facilitating integration of the experience into existing memories.

Intervention: Digital storytelling

Eligibility Criteria

Age13 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • (1) age between 13 and 18 years;
  • (2) able to speak Cantonese and read Chinese; and
  • (3) completed the active treatment of cancer.

You may not qualify if:

  • survivors with mental and behavioural problems documented in their medical records.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Hong Kong Polytechnic University,

Hong Kong, Hong Kong

RECRUITING

MeSH Terms

Conditions

NeoplasmsDepression

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehavior

Study Officials

  • Ka Yan Ho, phd

    The Hong Kong Polytechnic University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
associate professor

Study Record Dates

First Submitted

June 26, 2025

First Posted

July 4, 2025

Study Start

October 16, 2023

Primary Completion (Estimated)

September 12, 2026

Study Completion (Estimated)

September 12, 2026

Last Updated

March 12, 2026

Record last verified: 2026-03

Locations