Acute Effect of Motor-Cognitive Training

NCT06017154 | Completed

• 1 other identifier: 88851
• Study Type: interventional
• Target: 21
• Locations: 1 country
• Sites: 1

Brief Summary

Participants will complete a functional MRI to evaluate brain activation, functional connectivity, and behavioral performance immediately before and after a training program (approximately 30 minutes). The training program will comprise of integrate neuromuscular (agility, dynamic postural stability, shuffling, rapid acceleration/deceleration, plyometrics, lateral shuffle, and core stability) and cognitive (reaction time, processing speed, task switching, decision-making, and working memory) challenges.

Conditions

Injury;Sports

Keywords

injury prevention; cognition; physical performance; athletic training

Outcome Measures

Primary Outcomes (4)

• Change in brain activation

  During the task-based functional MRI scan the participant will complete a task-switching cognitive task, where participants have to identify two possible shapes (circle or square), in one of two possible colors (red or blue). They will respond using a trigger under their left and right foot. The level of brain activation during the task will be captured and reported.

  2 hours, pre-training session and immediately post-training session

• Change in functional connectivity

  The participant will complete a resting-state functional MRI scan in which they will lay still in the scanner. No task is performed during this scan. Functional connectivity (functionally related regions of the brain that are co-activated) during the scan will be captured and reported.

  2 hours, pre-training session and immediately post-training session

• Change in reaction time

  During the task-based functional MRI scan the participant will complete a task-switching cognitive task, where participants have to identify two possible shapes (circle or square), in one of two possible colors (red or blue). They will respond using a trigger under their left and right foot. The reaction time in milliseconds will be captured. The change in reaction time from pre to post training session will be reported.

  2 hours, pre-training session and immediately post-training session

• Change in accuracy

  During the task-based functional MRI scan the participant will complete a task-switching cognitive task, where participants have to identify two possible shapes (circle or square), in one of two possible colors (red or blue). They will respond using a trigger under their left and right foot. The percent of correct responses (accuracy) will be captured. The change in accuracy from pre to post training session will be reported.

  2 hours, pre-training session and immediately post-training session

Secondary Outcomes (11)

• Demographic/Injury History Form

  Once, pre-training

• Defense Veterans Pain Rating Scale

  Once, pre-training

• Modified Disablement In Physically Active Scale

  Once, pre-training

• NASA Physical Activity Survey

  Once, pre-training

• Heart rate

  35 minutes, during the training session

Study Arms (1)

Physically active females

EXPERIMENTAL

Healthy active females between 18 and 25

Other: Motor-Cognitive Training Program

Interventions

Motor-Cognitive Training Program OTHER

The training will incorporate cognitive tasks which focus on reaction time, processing speed, working memory, cognitive flexibility, and inhibitory control using visual stimuli on a screen or through sensors which illuminate using LED lights. These cognitive tasks will be performed while also executing physical performance tasks that challenge static and dynamic postural stability, lateral movement, agility, and other movement patterns. The training session will last approximately 30 minutes and participants will complete up to 5 exercises

Physically active females

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Physically active

You may not qualify if:

• Injury to the muscle or bone (upper extremity, lower extremity, or back) within the past 3 months
• Had musculoskeletal surgery or fracture (required open reduction internal fixation or within the last 12 months)
• Had a concussion or mild head injury within the last year
• Have been diagnosed with any kind of neurological, vestibular, or visual disturbance that impairs mobility
• Currently taking medications that affect the central nervous system
• Pregnant or suspicions of being pregnant
• Have metal fragments, pins, plates, or clips, shrapnel, body piercings that cannot be removed, have surgical implants or orthodontics that cannot be removed
• Have claustrophobia
• Have a history of cognitive impairment

Sponsors & Collaborators

• Ke'La H Porter: lead

Study Sites (1)

University of Kentucky

Lexington, Kentucky, 40506, United States

Location

MeSH Terms

Conditions

Athletic Injuries

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Officials

• Ke'La H Porter, MS

  University of Kentucky

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Research Analyst Principal

Study Record Dates

• First Submitted: August 18, 2023
• First Posted: August 30, 2023
• Study Start: September 17, 2023
• Primary Completion: February 5, 2024
• Study Completion: February 5, 2024
• Last Updated: April 15, 2024

Record last verified: 2024-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)