Role of MRI in Diagnosis of Postmenopausal Bleeding Causes

NCT06004908 | Unknown

• 1 other identifier: MR imaging in uterus
• Study Type: observational
• Target: 36
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of the study is to determine the diagnostic performance of MRI of endometrial pathology in postmenopausal women with postmenopausal bleeding

Conditions

Postmenopausal Bleeding

Outcome Measures

Primary Outcomes (1)

• comparison between pre-biopsy MRI based diagnosis and histopathological proved diagnosis in cases of post-menopausal vaginal bleeding

  anaylsis between pre-biopsy MRI based diagnosis and histopathological proved diagnosis in cases of post-menopausal vaginal bleeding

  baseline

Interventions

MRI DEVICE

a type of scan that uses strong magnetic field sand radio waves to produce detailed images of the inside of the body

Also known as: Magnetic resonance imaging

Eligibility Criteria

• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Any female patient after menopause suffering from vaginal bleeding

You may qualify if:

• Any female patient after menopause suffering from vaginal bleeding.
• Patients receiving tamoxifen with vaginal bleeding.
• Patient had histopathological biopsy examination either by total hysterectomy, hysteroscopy or D \&C.
• Patient must have local cause

You may not qualify if:

• \. Patients not amenable for MRI examination 2. Patients not in menopause 3. Patients have general bleeding tendency 4. Patients not underwent histopathological biopsy examination

Sponsors & Collaborators

• Assiut University: lead

Related Publications (4)

• Dubinsky TJ, Parvey HR, Maklad N. The role of transvaginal sonography and endometrial biopsy in the evaluation of peri- and postmenopausal bleeding. AJR Am J Roentgenol. 1997 Jul;169(1):145-9. doi: 10.2214/ajr.169.1.9207515.

  PMID: 9207515 BACKGROUND

• Karlsson B, Granberg S, Wikland M, Ylostalo P, Torvid K, Marsal K, Valentin L. Transvaginal ultrasonography of the endometrium in women with postmenopausal bleeding--a Nordic multicenter study. Am J Obstet Gynecol. 1995 May;172(5):1488-94. doi: 10.1016/0002-9378(95)90483-2.

  PMID: 7755059 BACKGROUND

• Gull B, Karlsson B, Milsom I, Granberg S. Can ultrasound replace dilation and curettage? A longitudinal evaluation of postmenopausal bleeding and transvaginal sonographic measurement of the endometrium as predictors of endometrial cancer. Am J Obstet Gynecol. 2003 Feb;188(2):401-8. doi: 10.1067/mob.2003.154.

  PMID: 12592247 BACKGROUND

• Foti PV, Tonolini M, Costanzo V, Mammino L, Palmucci S, Cianci A, Ettorre GC, Basile A. Cross-sectional imaging of acute gynaecologic disorders: CT and MRI findings with differential diagnosis-part II: uterine emergencies and pelvic inflammatory disease. Insights Imaging. 2019 Dec 20;10(1):118. doi: 10.1186/s13244-019-0807-6.

  PMID: 31858287 BACKGROUND

MeSH Terms

Interventions

Magnetic Resonance Imaging

Intervention Hierarchy (Ancestors)

Tomography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Officials

• Hossam ElDen Mustafa Kamel, MD

  unaffilitated

  PRINCIPAL INVESTIGATOR

Central Study Contacts

kholoud khaled salem, graduated

CONTACT

01050111754; Kkholod676@gmail.com

Mostafa Hashem Mahmoud othma, MD

CONTACT

01005618665; hashemradiol@yahoo.com

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant lecturer

Study Record Dates

• First Submitted: August 15, 2023
• First Posted: August 22, 2023
• Study Start: October 1, 2023
• Primary Completion: October 1, 2024
• Study Completion: November 1, 2024
• Last Updated: August 22, 2023

Record last verified: 2023-08