Endometrial Evaluation in Cases of Postmenopausal Bleeding

NCT03847415 | Unknown

• 1 other identifier: endometrial volume
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this prospective observational study is to evaluate abnormal uterine bleeding in postmenopausal women using 3D(dimensional) ultrasound assessment of endometrial volume .Doppler assessment of endometrium and hysteroscopy and to correlate this finding with pathological finding of endometrial biopsy

Conditions

Postmenopausal Bleeding

Outcome Measures

Primary Outcomes (1)

• accuracy of 3d ultrasound in post menopausal bleeding

  to evalute women with postmenpausal uterine bleeding using three dimensional ultrasound assessment of endometrial volume

  6months

Secondary Outcomes (1)

• comparison between hysteroscopy and ultrasound in post menopausal bleeding

  6months

Interventions

ultrasound DIAGNOSTIC_TEST

to evalute abnormal uterine bleeding in postmenopausal women using 3D(dimensional) ultrasound assessment of endometrial volume .Doppler assessment of endometrium and hysteroscopy and to correlate this finding with pathological finding of endometrial biopsy

Also known as: hysteroscopy, fractional currettage

Eligibility Criteria

• Age: 45 Years+
• Sex: female
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Women Age \> 45 years postmenopausal uterine bleeding

You may qualify if:

• Women Age \> 45 years
• with postmenopausal uterine bleeding

You may not qualify if:

• Women with bleeding disorders or coagulopathy
• women with cervical cancer or breast carcinoma .
• history of tamoxifen intake
• women with fibroid .

Sponsors & Collaborators

• Cairo University: lead

Related Publications (2)

• Goldstein SR. Modern evaluation of the endometrium. Obstet Gynecol. 2010 Jul;116(1):168-176. doi: 10.1097/AOG.0b013e3181dfd557.

  PMID: 20567184 BACKGROUND

• Jacobs I, Gentry-Maharaj A, Burnell M, Manchanda R, Singh N, Sharma A, Ryan A, Seif MW, Amso NN, Turner G, Brunell C, Fletcher G, Rangar R, Ford K, Godfrey K, Lopes A, Oram D, Herod J, Williamson K, Scott I, Jenkins H, Mould T, Woolas R, Murdoch J, Dobbs S, Leeson S, Cruickshank D, Skates SJ, Fallowfield L, Parmar M, Campbell S, Menon U. Sensitivity of transvaginal ultrasound screening for endometrial cancer in postmenopausal women: a case-control study within the UKCTOCS cohort. Lancet Oncol. 2011 Jan;12(1):38-48. doi: 10.1016/S1470-2045(10)70268-0. Epub 2010 Dec 10.

  PMID: 21147030 BACKGROUND

MeSH Terms

Interventions

Ultrasonography; Hysteroscopy

Intervention Hierarchy (Ancestors)

Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Diagnostic Techniques, Obstetrical and Gynecological; Endoscopy; Diagnostic Techniques, Surgical; Minimally Invasive Surgical Procedures; Surgical Procedures, Operative; Obstetric Surgical Procedures; Gynecologic Surgical Procedures; Urogenital Surgical Procedures

Central Study Contacts

Mohamed Reda, M.D

CONTACT

+201000769315; mo.reda2011@yahoo.com

Ahmed Aref

CONTACT

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assisant lecturer

Study Record Dates

• First Submitted: February 9, 2019
• First Posted: February 20, 2019
• Study Start: February 1, 2019
• Primary Completion: September 1, 2019
• Study Completion: October 1, 2019
• Last Updated: February 20, 2019

Record last verified: 2019-02