NCT06002191

Brief Summary

The objective of this study is to test the feasibility and preliminary efficacy of Flourish (formerly referred to as imHere4U), a digital suicide prevention intervention for cyberbullied adolescents. The specific aims are to: Aim #1: Conduct a randomized controlled trial (RCT) comparing Flourish+Questionnaires vs. Questionnaires Alone among cyberbullied youth at-risk for suicide ages 12-17 (N=80, \>35% underserved youth). H2a. Primary outcome: Feasibility will be evidenced by recruitment/retention rates \> 80% and imHere4U engagement \> 70%. H2b. Secondary outcomes: Youth assigned to Flourish+Questionnaires will report improved problem-solving capacity, distress tolerance, and motivation and reduced distress and suicidal ideation than youth assigned to Questionnaires Alone over the 6-month follow-up period. Exploratory Aim: Examine the feasibility of delivering feedback on online interactions from machine learning algorithms. All youth assigned to Flourish may optionally provide their social media data to receive feedback from machine learning algorithms. H3a. Feedback from algorithms will have high acceptability (identified via qualitative themes and \>70% acceptance rates) and usability, defined by mean scores on Post-Study System and Usability Questionnaire (PSSUQ) \> 6.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
3mo left

Started Nov 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress91%
Nov 2023Aug 2026

First Submitted

Initial submission to the registry

August 10, 2023

Completed
11 days until next milestone

First Posted

Study publicly available on registry

August 21, 2023

Completed
3 months until next milestone

Study Start

First participant enrolled

November 21, 2023

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2026

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2026

Expected
Last Updated

September 11, 2025

Status Verified

September 1, 2025

Enrollment Period

2.3 years

First QC Date

August 10, 2023

Last Update Submit

September 4, 2025

Conditions

Outcome Measures

Primary Outcomes (3)

  • Recruitment rates of eligible participants

    Feasibility will be measured through recruitment rates of eligible participants, using a cut-off score of 80% for desirable recruitment rates.

    Assessed upon recruitment to the study

  • Retention rates of eligible participants

    Feasibility will be measured through retention rates of eligible participants, using a cut-off score of 80% for desirable retention rates across the 12-week study period.

    Assessed upon completion of the Week 12 study visits

  • Level of intervention usage

    Usage of the intervention will be assessed by engagement with the text messaging intervention one or more times during the study period. A cut-off score of 70% of youth using the intervention one or more times will be used as a minimum requirement for acceptable usage.

    Assessed upon completion of the 4-week intervention period

Secondary Outcomes (6)

  • Change in psychological distress from baseline to 4 weeks

    Assessed at the baseline and Week 4 follow-up assessment visits

  • Change in psychological distress from baseline to 12 weeks

    Assessed at the Week 12 follow-up assessment visits

  • Change in severity of suicidal ideation and behavior from baseline to 4 weeks

    Assessed at baseline and Week 4 follow-up assessment visits

  • Change in severity of suicidal ideation and behavior from baseline to 12 weeks

    Assessed at baseline and Week 12 follow-up assessment visits

  • Change in suicidal ideation from baseline to 4 weeks

    Assessed at the baseline and Week 4 assessment visits

  • +1 more secondary outcomes

Other Outcomes (6)

  • Change in distress tolerance from baseline to 4 weeks

    Assessed at the baseline and Week 4 assessment visits

  • Change in distress tolerance from baseline to 12 weeks

    Assessed at the baseline and Week 12 assessment visit

  • Change in motivation for help-seeking from baseline to 4 weeks

    Assessed at the baseline and Week 4 assessment visits

  • +3 more other outcomes

Study Arms (2)

Flourish + Questionnaires

EXPERIMENTAL

Participants will be onboarded to Flourish by a research study clinician, following which they will receive a text messaging program for 4 weeks as well as an accompanying resources website. As part of the text messaging program, participants will receive brief questionnaires evaluating their online experiences once every 3 days.

Behavioral: FlourishBehavioral: Questionnaires of Online Experiences

Questionnaires Alone

ACTIVE COMPARATOR

Participants will be onboarded to a text message program that solely will send participants brief questionnaires evaluating their online experiences once every 3 days.

Behavioral: Questionnaires of Online Experiences

Interventions

FlourishBEHAVIORAL

Flourish is a text messaging program that aims to improve coping following cyberbullying and reduce suicide risk among youth.

Flourish + Questionnaires

Adolescents will receive brief questionnaires related to their online experiences and the impact those experiences have had on their stress level.

Flourish + QuestionnairesQuestionnaires Alone

Eligibility Criteria

Age12 Years - 17 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • English-speaking
  • access to a phone or device capable of text messaging
  • past 3-month history of cyberbullying assessed by the cybervictimization subscale of the Traditional Bullying and Cyberbullying Victimization and Perpetration Scale and/or presence of online discrimination measured by a modified version of a discrimination measured developed as part of the Adolescent Brain and Cognitive Development (ABCD) study
  • past 3-month history of suicidal risk, including: psychological distress (\>13 on the 6-item Kessler Psychological Distress Scale) and/or suicidal ideation or behavior (via the Columbia Suicide Severity Rating Scale)

You may not qualify if:

  • intellectual challenges, low literacy levels, or other conditions that might inhibit adolescents' ability to effectively engage with Flourish (reported by parents and, if needed, confirmed through the age-appropriate Wechsler Intelligence scale)
  • acuity levels suggesting need for a higher level of care (e.g., inpatient hospitalization) or referral for emergency services

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15213, United States

RECRUITING

MeSH Terms

Conditions

Suicidal Ideation

Condition Hierarchy (Ancestors)

SuicideSelf-Injurious BehaviorBehavioral SymptomsBehavior

Study Officials

  • Candice L Biernesser, PhD

    University of Pittsburgh

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Candice L Biernesser, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: The study design is a randomized controlled trial.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor of Psychiatry

Study Record Dates

First Submitted

August 10, 2023

First Posted

August 21, 2023

Study Start

November 21, 2023

Primary Completion

March 1, 2026

Study Completion (Estimated)

August 1, 2026

Last Updated

September 11, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will share

De-identified data from enrolled participants may be shared with investigators within and outside of the University of Pittsburgh and University of Pittsburgh Medical Center for the purpose of studying cyberbullying or suicide risk among adolescents. Data sharing will be consistent with International Committee of Medical Journal Editors (ICMJE) requirements.

Shared Documents
STUDY PROTOCOL
Time Frame
These data will be released following acceptance of the project's main outcomes manuscript.
Access Criteria
Data requests may be sent to the PI for review, who will provide data to interested and qualified investigators.

Locations