Effect of Life Kinetik Training on Lower Limb Coordination in Ataxic Patients

NCT06001424 | Completed

• 1 other identifier: P.T.REC/012/001987
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Coordination is essential for the performance of most daily motor activities. Coordination problems are common in MS patients. One of the most commonly reported symptoms is dysmetria (limb ataxia). Ataxia is thought to occur in about 80% of MS patients. It leads to limitations in daily life activities. Aim of Study: to investigate the effect of life kinetik training on lower limb coordination in MS patients with ataxia.

Conditions

Multiple Sclerosis; Ataxia

Keywords

Multiple Sclerosis; ataxia; coordination; life kinetic exercises

Outcome Measures

Primary Outcomes (2)

• Lower Extremity Motor Coordination Test (LEMOCOT)

  test to assess lower limb coordination

  at baseline

• Lower Extremity Motor Coordination Test (LEMOCOT)

  test to assess lower limb coordination

  post intervention (after one month)

Secondary Outcomes (2)

• Four Square Step Test (FSST)

  at baseline

• Four Square Step Test (FSST)

  post intervention (after one month)

Study Arms (2)

study group

EXPERIMENTAL

will receive physical therapy program of in addition to life kinetik training.

Other: physical therapy; Other: life kinetic exercises

control

ACTIVE COMPARATOR

will receive physical therapy program

Other: physical therapy

Interventions

physical therapy OTHER

Frenkel's exercises for lower limb, Proprioceptive neuromuscular facilitation for upper limb in the form of rhythmic stabilization

control; study group

life kinetic exercises OTHER

A multimodal training that combines coordinative, cognitive and visual tasks.

study group

Eligibility Criteria

• Age: 20 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• MS from both sexes
• Patients' age will be ranged from 20 to 45 years
• Expanded disability scale (EDSS) score ranging from "two" to "four"

You may not qualify if:

• Patients with Ataxia caused by other cause rather than MS
• Patients with other neurological disease or orthopedic deformities may affect movement
• Patients with cardiovascular and pulmonary diseases that make exercise unsafe
• Patients with cognitive impairment or psychiatric disorders

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Physical Therapy

Giza, 11432, Egypt

Location

Related Publications (1)

• Edwards EM, Fritz NE, Therrien AS. Cerebellar Dysfunction in Multiple Sclerosis: Considerations for Research and Rehabilitation Therapy. Neurorehabil Neural Repair. 2022 Feb;36(2):103-106. doi: 10.1177/15459683211065442. Epub 2021 Dec 21.

  PMID: 34931569 BACKGROUND

MeSH Terms

Conditions

Multiple Sclerosis; Ataxia

Interventions

Physical Therapy Modalities

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases; Dyskinesias; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Therapeutics; Rehabilitation

Study Officials

• Moshera H Darwish, Prf. Dr

  Professor of Physical therapy for Neurology

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Ass. Prof. Dr. of Physical therapy for Neurology

Model Details: randomized controlled trail

Study Record Dates

• First Submitted: January 17, 2021
• First Posted: August 21, 2023
• Study Start: June 24, 2018
• Primary Completion: April 30, 2021
• Study Completion: May 29, 2021
• Last Updated: August 21, 2023

Record last verified: 2023-08

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)