Effectiveness Of The Pericapsular Nerve Group (PENG) Block In Hip Surgery

NCT05997940 | Unknown

• 1 other identifier: 2022/03
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The target population of hip surgery is usually the elderly patients with systemic comorbidity. Especially hip fractures are common in society and cause high morbidity and mortality for geriatric patients . Pain felt before and during surgery can cause metabolic and endocrine changes in the body, leading to sleep disorders, depression, delirium, dementia and persistent chronic pain. With effective postoperative analgesia, it is possible to reduce postoperative complications and mortality and accelerate post-surgical recovery. Pharmacological methods such as opioids and NSAIDs used for this may cause further deterioration and other side effects in geriatric patients with reduced renal and hepatic function, thus delaying post-surgical recovery and thus discharge. In order to avoid these side effects, regional anesthesia techniques can be preferred. Regional anesthesia techniques are among the most effective methods of postoperative analgesia. Peripheral nerve blocks are also one of the regional anesthesia methods. Peripheral nerve blocks; They are the most ideal postoperative analgesia methods because they provide effective analgesia, reduce the need for opioids and consequently their side effects, are effective in the treatment of dynamic pain and facilitate recovery. Patients undergoing hip surgery have very severe pain and need additional postoperative analgesics. Mobilization of patients is delayed due to pain . Depending on this , thromboembolism , deep vein The risk of nosocomial infection increases due to thrombosis , wound infection and increased length of stay. Alleviating the pain around the hip joint capsule is an effective analgesia method in hip surgeries. The anterior capsule of the hip joint is innervated by the femoral , obturator , and accessory obturator nerves . Pericapsular nerve group (PENG) block also targets these nerves. Many studies have shown that PENG block provides adequate analgesia for more than 24 hours postoperatively. PENG block is a method that is frequently used in the world and in our clinic and has a low complication rate. In this study, the investigators aimed to show that pericapsular nerve group block performed before spinal anesthesia in hip surgeries reduces postoperative pain and decreases total opioid consumption.

Conditions

PENG Block

Keywords

Pericapsular nerve group (PENG) block; Postoperative analgesia; Hip Surgery; Regional anesthesia; Spinal anesthesia

Outcome Measures

Primary Outcomes (7)

• Numeric Rating Scale (NRS) for postoperative analgesic efficacy

  NRS is a one-dimensional scale used to measure pain intensity. The patient is asked to select the number that best describes the level of pain as 0 = no pain and 10 = worst pain (unbearable).

  Preoperative

• Numeric Rating Scale (NRS) for postoperative analgesic efficacy

  NRS is a one-dimensional scale used to measure pain intensity. The patient is asked to select the number that best describes the level of pain as 0 = no pain and 10 = worst pain (unbearable).

  During the spinal anesthesia

• Numeric Rating Scale (NRS) for postoperative analgesic efficacy

  NRS is a one-dimensional scale used to measure pain intensity. The patient is asked to select the number that best describes the level of pain as 0 = no pain and 10 = worst pain (unbearable).

  Postoperative 0. hour

• Numeric Rating Scale (NRS) for postoperative analgesic efficacy

  NRS is a one-dimensional scale used to measure pain intensity. The patient is asked to select the number that best describes the level of pain as 0 = no pain and 10 = worst pain (unbearable).

  Postoperative 1. hour

• Numeric Rating Scale (NRS) for postoperative analgesic efficacy

  NRS is a one-dimensional scale used to measure pain intensity. The patient is asked to select the number that best describes the level of pain as 0 = no pain and 10 = worst pain (unbearable).

  Postoperative 6. hour

• Numeric Rating Scale (NRS) for postoperative analgesic efficacy

  NRS is a one-dimensional scale used to measure pain intensity. The patient is asked to select the number that best describes the level of pain as 0 = no pain and 10 = worst pain (unbearable).

  Postoperative 12. hour

• Numeric Rating Scale (NRS) for postoperative analgesic efficacy

  NRS is a one-dimensional scale used to measure pain intensity. The patient is asked to select the number that best describes the level of pain as 0 = no pain and 10 = worst pain (unbearable).

  Postoperative 24. hour

Secondary Outcomes (1)

• Amounts of postoperative analgesic consumption

  Postoperative 24 hours

Study Arms (2)

PENG

ACTIVE COMPARATOR

PENG block performed before spinal anesthesia

Drug: PENG block

Control

NO INTERVENTION

Interventions

PENG block DRUG

The PENG block was performed with the patient in the supine position at preoperative waiting room. A curvilinear low-frequency ultrasound probe (2-5 MHz) was initially placed in a transverse plane over the AIIS and then aligned with the pubic ramus by rotating the probe counterclockwise approximately 45 degrees. In this view, the IPE, the iliopsoas muscle and tendon, the femoral artery, and pectineus muscle were observed. A 22 gauge, 100 mm needle was inserted from lateral to medial in an in-plane approach to place the tip in the musculofascial plane between the psoas tendon anteriorly and the pubic ramus posteriorly. Following negative aspiration, the local anesthetic solution was injected in 5 mL increments while observing for adequate fluid spread in this plane for a total volume of 20 mL

PENG

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with written informed consent
• Patients over 18 years old
• Patients with ASA score I-II-III
• Patients performed spinal anesthesia for surgery

You may not qualify if:

• Patients without written informed consent
• Patients with ASA score IV and above
• Patients who cannot be communicated
• Patients with infection at the block site
• Patients with coagulation disorders
• Patients not suitable for spinal anesthesia
• Patients with liver and kidney failure
• Patients who are allergic to the drugs used
• Patients with major complications during the operation

Sponsors & Collaborators

• Aydin Adnan Menderes University: lead

Study Sites (1)

Adnan Menderes University Faculty of Medicine

Aydin, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Bites and Stings

Condition Hierarchy (Ancestors)

Poisoning; Chemically-Induced Disorders; Wounds and Injuries

Central Study Contacts

Kadir Berkay TAN, Resident Doctor

CONTACT

+905393506273; k.berkay.tan@adu.edu.tr

Mustafa OGURLU, Professor Doctor

CONTACT

+905326056932; mogurlu@adu.edu.tr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor Doctor

Study Record Dates

• First Submitted: July 11, 2023
• First Posted: August 18, 2023
• Study Start: October 1, 2022
• Primary Completion: August 15, 2023
• Study Completion: September 1, 2023
• Last Updated: August 18, 2023

Record last verified: 2023-08

Locations

TU (1)