Effect of PENG Block on Postoperative Tramadol Consumption in Partial Hip Prosthesis Surgery

NCT07534137 | Completed

• 1 other identifier: GAUN-2022-248
• Study Type: interventional
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the effect of ultrasound-guided pericapsular nerve group (PENG) block on postoperative tramadol consumption, pain scores, and clinical outcomes in patients undergoing partial hip prosthesis surgery. Patients aged 18-75 years scheduled for surgery under general anesthesia were divided into two groups: those receiving PENG block and those not receiving the block. Postoperative tramadol consumption within the first 24 hours, visual analog scale (VAS) and numeric rating scale (NRS) scores, hemodynamic parameters, additional analgesic requirements, and recovery characteristics were recorded and compared between groups. The findings of this study are expected to contribute to optimizing multimodal analgesia strategies in hip surgery.

Conditions

Hip Fracture; Postoperative Pain

Keywords

peng block; Pericapsular nerve group block; Hip surgery; Postoperative pain; Tramadol consumption; Regional anesthesia

Outcome Measures

Primary Outcomes (1)

• Total Tramadol Consumption Within 24 Hours After Surgery

  Total amount of tramadol (mg) consumed by patients during the first 24 hours after surgery.

  24 hours postoperatively

Secondary Outcomes (5)

• Postoperative VAS Pain Scores

  0, 10, 30, 60 minutes and 2, 4, 6, 12, 24 hours postoperatively

• Postoperative NRS Pain Scores

  0, 10, 30, 60 minutes and 2, 4, 6, 12, 24 hours postoperatively

• Intraoperative Remifentanil Consumption

  Intraoperative period

• Additional Analgesic Requirement

  24 hours postoperatively

• Postoperative Complications

  24 hours postoperatively

Study Arms (2)

PENG Block Group

EXPERIMENTAL

Patients receiving ultrasound-guided PENG block after induction of general anesthesia.

Procedure: PENG Block

Control Group

ACTIVE COMPARATOR

Control Group

Procedure: General Anesthesia

Interventions

PENG Block PROCEDURE

Ultrasound-guided pericapsular nerve group block performed with 20 mL of 0.5% bupivacaine after induction of general anesthesia.

PENG Block Group

General Anesthesia PROCEDURE

Standard general anesthesia administered without regional nerve block.

Control Group

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients aged between 18 and 75 years
• Patients scheduled for partial hip prosthesis surgery
• Patients classified as ASA physical status I-III
• Patients who provided written informed consent

You may not qualify if:

• Known allergy to local anesthetics
• Coagulation disorders or anticoagulant therapy contraindicating regional anesthesia
• Infection at the injection site
• Severe systemic disease (ASA IV or higher)
• Cognitive impairment preventing reliable pain assessment
• Refusal to participate in the study

Sponsors & Collaborators

• University of Gaziantep: lead

Study Sites (1)

Gaziantep University Faculty Of Medicine

Gaziantep, 27310, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Hip Fractures; Pain, Postoperative

Interventions

Anesthesia, General

Condition Hierarchy (Ancestors)

Femoral Fractures; Fractures, Bone; Wounds and Injuries; Hip Injuries; Leg Injuries; Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Anesthesia; Anesthesia and Analgesia

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: No masking was applied in this study.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Assistant in Anesthesiology

Model Details: Participants were randomly assigned to two parallel groups: a PENG block group receiving ultrasound-guided pericapsular nerve group block after induction of general anesthesia, and a control group receiving general anesthesia alone.

Study Record Dates

• First Submitted: April 9, 2026
• First Posted: April 16, 2026
• Study Start: March 1, 2022
• Primary Completion: October 1, 2022
• Study Completion: December 1, 2022
• Last Updated: April 16, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)