A Prospective Longitudinal Study in Adults With Multifocal Motor Neuropathy
iMMersioN
A Multicenter Prospective Longitudinal Study of Clinical Outcomes, Disease Course, Health-Related Quality of Life, and Health Care Resource Utilization in Adult Patients With Multifocal Motor Neuropathy
1 other identifier
observational
413
18 countries
108
Brief Summary
This prospective longitudinal study will follow participants with Multifocal Motor Neuropathy over time and collect data on their clinical outcomes, quality of life, and use of health care resources. Participants will follow their regular visit schedule with their treating physician, except for an optional second visit occurring 7 to 14 days after the start of the study to collect biomarker data. No IMP will be administered.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2023
Longer than P75 for all trials
108 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 4, 2023
CompletedFirst Posted
Study publicly available on registry
August 14, 2023
CompletedStudy Start
First participant enrolled
November 29, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2028
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 31, 2028
March 16, 2026
March 1, 2026
5.1 years
August 4, 2023
March 13, 2026
Conditions
Outcome Measures
Primary Outcomes (6)
To characterize MMN patient profiles for participants
up to 61 months
To assess the MMN disease management and disease course
up to 61 months
To assess outcome measures specific to MMN disease and their evolution over time
up to 61 months
To estimate the burden of MMN on participants' quality of life
up to 61 months
To estimate the economic burden for participants with MMN
up to 61 months
To collect data on relevant disease biomarkers
up to 61 months
Eligibility Criteria
Patients with MMN receiving standard of care at their treating physician.
You may qualify if:
- Is at least the local legal age of consent for clinical studies when signing the ICF
- Is capable of providing signed informed consent and complying with protocol requirements
- Has an existing or new diagnosis of MMN made by a neuromuscular specialist or neurologist
You may not qualify if:
- Is currently participating in any clinical study with an IMP
- Has other medical conditions that could affect the assessment of MMN
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- argenxlead
Study Sites (113)
Neuromuscular Clinical and Research Center
Phoenix, Arizona, 85028, United States
HonorHealth Neurology - Bob Bove Neuroscience Institute
Scottsdale, Arizona, 85251, United States
UCI Health - ALS and Neuromuscular Center
Orange, California, 92868, United States
Stanford Medicine Health Care - Stanford Neuroscience Health Center
Palo Alto, California, 94304, United States
The Neurology Group
Pomona, California, 91767-2009, United States
Eisenhower Health - Rancho Mirage Medical Center
Rancho Mirage, California, 92270, United States
UC Davis Health - Lawrence J. Ellison Ambulatory Care Center
Sacramento, California, 95817-2307, United States
UCSF Health - UCSF Medical Center
San Francisco, California, 94143-2204, United States
University of Colorado - Anschutz Medical Campus
Aurora, Colorado, 80045, United States
YaleNewHavenHealth - Yale New Haven Hospital
New Haven, Connecticut, 06520, United States
Medsol Clinical Research Center Inc
Port Charlotte, Florida, 33952, United States
D&H National Research Centers - Tamarac Research Center
Tamarac, Florida, 33321, United States
Hospital Sisters Health System (HSHS) - St Elizabeth's Hospital
O'Fallon, Illinois, 62269, United States
The University of Kansas Health System - Landon Center on Aging
Kansas City, Kansas, 66103, United States
MedStar Georgetown University Hospital
Chevy Chase, Maryland, 20815-6902, United States
Rutgers University - Robert Wood Johnson Medical School
New Brunswick, New Jersey, 08901, United States
Columbia University Irving Medical Center - Neurological Institute of New York
New York, New York, 10032, United States
University of North Carolina - Chapel Hill
Chapel Hill, North Carolina, 27599-7025, United States
Ohio State University Wexner Medical Center - Ohio State Martha Morehouse Outpatient Care
Columbus, Ohio, 43221-3502, United States
Oregon Health and Science University (OHSU) Hospital - Marquam Hill Campus
Portland, Oregon, 97239, United States
Penn Medicine - Penn Medicine University City
Philadelphia, Pennsylvania, 19104, United States
Penn Medicine - Perelman Center for Advanced Medicine
Philadelphia, Pennsylvania, 19104, United States
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
Northwest Houston Neurology - Cypress
Cypress, Texas, 77429, United States
Royal Melbourne Hospital
Parkville, 3050, Australia
Gold Coast University Hospital
Southport, 4215, Australia
Princess Alexandra Hospital
Woolloongabba, 4102, Australia
Allgemeines Krankenhaus der Stadt Wien (AKH Wien)
Vienna, 1090, Austria
Hopital Erasme
Brussels, 1070, Belgium
Universitair Ziekenhuis Antwerpen
Edegem, 2650, Belgium
Universitair Ziekenhuis Gent
Ghent, 9000, Belgium
Universitair Ziekenhuis Brussel
Jette, 1090, Belgium
Universitair Ziekenhuis Leuven - Campus Gasthuisberg
Leuven, 3000, Belgium
L'hopital de la Citadelle - Site Citadelle
Liège, 4000, Belgium
Cliniques Universitaires Saint-Luc
Woluwe-Saint-Lambert, 1200, Belgium
Multiprofile Hospital for Active Treatment - Uni Hospital OOD
Panagyurishte, 4500, Bulgaria
Medical Center Medconsult Pleven OOD
Pleven, 5800, Bulgaria
Military Medical Academy - Military Hospital for Active Treatment Pleven
Pleven, 5800, Bulgaria
University Multiprofile Hospital for Active Treatment and Emergency Medicine N. I. Pirogov
Sofia, 1606, Bulgaria
London Health Sciences Centre - University Hospital
London, N6A 5A5, Canada
Centre Hospitalier de l'Universite de Montreal
Montreal, H2X 0C1, Canada
McGill University Health Centre - The Neuro (Montreal Neurological Institute-Hospital)
Montreal, H3A 2B4, Canada
CHU de Quebec - Hopital de L'enfant Jesus
Québec, G1J 1Z4, Canada
University of Saskatchewan - University of Saskatchewan College of Medicine
Saskatoon, S7H 0G9, Canada
Xiangya Hospital of Central South University
Changsha, 410008, China
The First Affiliated Hospital of Nanchang University
Nanchang, 330006, China
Huashan Hospital of Fudan University
Shanghai, China
Fakultni nemocnice Brno - Areal Bohunice
Brno, 62500, Czechia
Fakultni nemocnice Hradec Kralove
Hradec Králové, 500 05, Czechia
Aarhus Universitetshospital
Aarhus, 8200, Denmark
Rigshospitalet - Blegdamsvej
Copenhagen, 2100, Denmark
CHU Angers
Angers, 49933, France
CHU de Bordeaux - Hôpital Pellegrin
Bordeaux, 33000, France
CHU Brest - Hopital La Cavale Blanche
Brest, 29200, France
Hospices Civils de Lyon (HCL) - Hopital Pierre Wertheimer
Bron, 69500, France
Assistance Publique Hopitaux de Paris (AP-HP) - Hopital Bicetre
Le Kremlin-Bicêtre, 94270, France
CHU Lille - Hopital Salengro
Lille, 59037, France
CHU de Limoges - CHU Dupuytren 1
Limoges, 87042, France
AP-HM - CHU Timone
Marseille, 13385, France
CHU de Nantes - Hotel Dieu
Nantes, 44093, France
CHU de Nice - Hopital Pasteur
Nice, 06001, France
Assistance Publique Hopitaux de Paris (AP-HP) - Hopital Pitie-Salpetriere
Paris, 75013, France
Universitatsklinikum Essen
Essen, 45147, Germany
Universitatsklinikum Giessen und Marburg - Campus Giessen
Giessen, 35385, Germany
Medizinische Hochschule Hannover
Hanover, 30625, Germany
St. Josefs- Krankenhaus Potsdam- Sanssouci
Potsdam, 14471, Germany
Universitatsklinikum Wurzburg
Würzburg, 97080, Germany
Azienda Ospedaliero Universitaria Careggi
Florence, 50134, Italy
Fondazione Serena Onlus - NeMO Brescia
Gussago, 25064, Italy
Azienda Ospedaliera Universitaria Gaetano Martino
Messina, 98125, Italy
Universita degli Studi del Piemonte Orientale Amedeo Avogadro - Scuola di Medicina
Novara, 28100, Italy
Azienda Ospedaliero-Universitaria San Luigi Gonzaga
Orbassano, 10043, Italy
Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone
Palermo, 90129, Italy
Istituto Neurologico Nazionale a Carattere Scientifico IRCCS
Pavia, 27100, Italy
Azienda Ospedaliero Universitaria Pisana - Ospedale Santa Chiara
Pisa, 56126, Italy
Azienda Ospedaliero Universitaria Sant'Andrea
Roma, 00189, Italy
Fondazione PTV Policlinico Tor Vergata
Roma, 133, Italy
Teikyo University Hospital
Itabashi-ku, 173-8606, Japan
National Center of Neurology and Psychiatry
Kodaira-shi, 187-8551, Japan
Dokkyo Medical University Hospital
Mibu, 321-0293, Japan
Riga East Clinical University Hospital
Riga, 1038, Latvia
Pauls Stradins Clinical University Hospital
Riga, LV-1002, Latvia
Medicover Integrated Clinical Services (MICS) - Centrum Medyczne Bydgoszcz
Bydgoszcz, 85-065, Poland
Wielospecjalistyczna Poradnia Lekarska Synapsis
Katowice, 40-123, Poland
Specjalistyczne Gabinety Sp. z o.o.
Krakow, 30-539, Poland
Michalski i Partnerzy Lekarze Spolka Partnerska
Krakow, 31-426, Poland
SP ZOZ Szpital Uniwersytecki w Krakowie
Krakow, 31-503, Poland
CLINIREM Sp z o.o.
Lublin, 20-093, Poland
Rejdak Konrad Indywidualna Praktyka Lekarska
Lublin, 20-605, Poland
Centrum Medyczne Hope Clinic
Lublin, 20-701, Poland
ETG Network - ETG Neuroscience
Warsaw, 02-677, Poland
Spitalul Clinic Judetean de Urgenta Sf. Apostol Andrei
Constanța, 900591, Romania
Univerzitetski klinicki centar Srbije
Belgrade, 11000, Serbia
Univerzitetski klinicki centar Kragujevac
Kragujevac, 34000, Serbia
Hospital General Universitario Dr. Balmis
Alicante, 03010, Spain
Hospital Universitari Germans Trias i Pujol (HUGTP)
Badalona, 08916, Spain
Hospital de la Santa Creu i Sant Pau
Barcelona, 08041, Spain
Hospital Universitario de Basurto
Bilbao, 48013, Spain
Hospital Universitari de Bellvitge
L'Hospitalet de Llobregat, 08907, Spain
Hospital Universitario Central de Asturias
Oviedo, 33011, Spain
Hospital Universitario de Navarra
Pamplona, 31008, Spain
Hospital Universitario de Donostia
San Sebastián, 20014, Spain
Sahlgrenska Universitetssjukhuset - MS - mottagning Sahlgrenska
Gothenburg, 413 45, Sweden
Karolinska Universitetssjukhuset - Huddinge
Huddinge, 141 57, Sweden
North Bristol NHS Trust - Southmead Hospital Bristol
Bristol, BS10 5NB, United Kingdom
Lancashire Teaching Hospitals NHS Foundation Trust - Royal Preston Hospital
Fulwood, PR2 9HT, United Kingdom
NHS Great Glasgow and Clyde - Queen Elizabeth University Hospital
Glasgow, G51 4TF, United Kingdom
Nottingham University Hospitals NHS Trust - Queen's Medical Centre
Nottingham, NG7 2UH, United Kingdom
Oxford University Hospitals NHS Foundation Trust - John Radcliffe Hospital
Oxford, OX3 9DU, United Kingdom
Northern Care Allicance NHS Foundation Trust - Salford Royal
Salford, M6 8HD, United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust - Royal Hallamshire Hospital
Sheffield, S10 2JF, United Kingdom
Somerset NHS Foundation Trust - Musgrove Park Hospital
Taunton, TA1 5DA, United Kingdom
Royal Cornwall Hospitals NHS Trust - Royal Cornwall Hospital
Truro, TR1 3LJ, United Kingdom
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 4, 2023
First Posted
August 14, 2023
Study Start
November 29, 2023
Primary Completion (Estimated)
December 31, 2028
Study Completion (Estimated)
December 31, 2028
Last Updated
March 16, 2026
Record last verified: 2026-03