Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 30/100

Failure Rate

9.4%

9 terminated/withdrawn out of 96 trials

Success Rate

80.0%

-6.6% vs industry average

Late-Stage Pipeline

32%

31 trials in Phase 3/4

Results Transparency

56%

20 of 36 completed trials have results

Key Signals

26 recruiting20 with results6 terminated

Enrollment Performance

Analytics

Phase 2
33(37.9%)
Phase 3
27(31.0%)
Phase 1
23(26.4%)
Phase 4
4(4.6%)
87Total
Phase 2(33)
Phase 3(27)
Phase 1(23)
Phase 4(4)

Activity Timeline

Global Presence

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Clinical Trials (96)

Showing 20 of 96 trials
NCT06298552Phase 3Active Not Recruiting

A Phase 3 Study to Evaluate the Efficacy and Safety of Efgartigimod IV in Patients With Acetylcholine Receptor Binding Antibody Seronegative Generalized Myasthenia Gravis

Role: lead

NCT07583641Phase 2Not Yet Recruiting

A Study to Learn About How Well the Medicine Efgartigimod Works to Treat Autoimmune Encephalitis In Children 12 Years or Older and Adults

Role: lead

NCT07287982Phase 2Recruiting

A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

Role: lead

NCT07746089Phase 3Not Yet Recruiting

A Study to Assess Efficacy and Safety of Adimanebart in Adult and Pediatric Participants With DOK7-,MUSK-, AGRN-, or LRP4- Congenital Myasthenic Syndromes (CMS)

Role: lead

NCT07284420Phase 2Recruiting

ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

Role: lead

NCT07294170Recruiting

ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis

Role: lead

NCT07673627Phase 2Recruiting

ADAPT Forward 2 - ISA2 - a Study to Evaluate the Safety, Tolerability and Efficacy of Empasiprubart IV Monotherapy in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis

Role: lead

NCT06436742Phase 1Active Not Recruiting

A Phase 1b Study to Investigate Safety and Tolerability of ARGX-119 in Adult Participants With DOK7-Congenital Myasthenic Syndromes (CMS)

Role: lead

NCT05523167Phase 2Completed

A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy.

Role: lead

NCT07091630Phase 3Recruiting

A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP

Role: lead

NCT06078553Recruiting

A Natural History Study in Participants With Congenital Myasthenic Syndromes (CMS) Due to Mutations in DOK7, MUSK, AGRN, or LRP4

Role: lead

NCT06655155Phase 2Recruiting

A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis

Role: lead

NCT06920004Phase 3Recruiting

A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP

Role: lead

NCT05979441Phase 3Enrolling By Invitation

A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy

Role: lead

NCT07194850Phase 2Recruiting

A Study of Efgartigimod IV in Participants From 12 Years to Less Than 18 Years of Age With Chronic Immune Thrombocytopenia (ITP)

Role: lead

NCT07596849Phase 3Recruiting

A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease.

Role: lead

NCT07570316Phase 3Recruiting

A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease

Role: lead

NCT06558279Phase 3Active Not Recruiting

A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC in Adults With Ocular Myasthenia Gravis

Role: lead

NCT06503731Phase 2Active Not Recruiting

A Study to Evaluate the Safety and Tolerability of Efgartigimod PH20 SC Given by Prefilled Syringe in Kidney Transplant Recipients With Antibody-Mediated Rejection (AMR)

Role: lead

NCT07673601Phase 1Recruiting

A Study to Assess the Absolute Bioavailability and How Adimanebart SC Moves Through the Body in Healthy Adult Participants

Role: lead