Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 40/100

Failure Rate

10.3%

9 terminated/withdrawn out of 87 trials

Success Rate

79.5%

-7.0% vs industry average

Late-Stage Pipeline

33%

29 trials in Phase 3/4

Results Transparency

49%

17 of 35 completed trials have results

Key Signals

23 recruiting17 with results6 terminated

Enrollment Performance

Analytics

Phase 2
30(38.0%)
Phase 3
25(31.6%)
Phase 1
20(25.3%)
Phase 4
4(5.1%)
79Total
Phase 2(30)
Phase 3(25)
Phase 1(20)
Phase 4(4)

Activity Timeline

Global Presence

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Clinical Trials (87)

Showing 20 of 87 trials
NCT07570316Phase 3Not Yet Recruiting

A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease

Role: lead

NCT07011589Phase 1Not Yet Recruiting

Targeting Collagen VII Antibodies in Bullous Diseases Using Efgartigimod IV (VYVGART)

Role: collaborator

NCT06544499Phase 3Recruiting

A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia

Role: lead

NCT06392386Phase 2Recruiting

A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age With Generalized Myasthenia Gravis

Role: lead

NCT06078553Recruiting

A Natural History Study in Participants With Congenital Myasthenic Syndromes (CMS) Due to Mutations in DOK7, MUSK, AGRN, or LRP4

Role: lead

NCT06436742Phase 1Recruiting

A Phase 1b Study to Investigate Safety and Tolerability of ARGX-119 in Adult Participants With DOK7-Congenital Myasthenic Syndromes (CMS)

Role: lead

NCT05374590Phase 2Enrolling By Invitation

Evaluating Long-term Safety of Efgartigimod Administered Intravenously and Efgartigimod PH20 Administered Subcutaneously in Children With Generalized Myasthenia Gravis

Role: lead

NCT06968338Phase 1Completed

A Study to Assess the Safety of ARGX-213 in Healthy Volunteers

Role: lead

NCT06655155Phase 2Recruiting

A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis

Role: lead

NCT07284420Phase 2Recruiting

ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

Role: lead

NCT05979441Phase 3Enrolling By Invitation

A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy

Role: lead

NCT07294170Recruiting

ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis

Role: lead

NCT07264426Recruiting

Real-World Efgartigimod Effectiveness in CIDP: A Prospective Study

Role: lead

NCT07287982Phase 2Recruiting

A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

Role: lead

NCT07194850Phase 2Recruiting

A Study of Efgartigimod IV in Participants From 12 Years to Less Than 18 Years of Age With Chronic Immune Thrombocytopenia (ITP)

Role: lead

NCT06920004Phase 3Recruiting

A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP

Role: lead

NCT06684847Phase 3Active Not Recruiting

A Study of the Efficacy and Safety of Efgartigimod in Patients With Primary Sjögren's Syndrome

Role: lead

NCT06441682Phase 2Active Not Recruiting

A Safety and Efficacy Study of ARGX-119 in Adult Patients With Amyotrophic Lateral Sclerosis (ALS)

Role: lead

NCT04777734Unknown

Pre-Approval Access for Efgartigimod PH20 SC in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Role: lead

NCT05907096Phase 2Active Not Recruiting

ARGX-117 in Deceased Donor Kidney Transplant Recipients at Risk for Delayed Graft Function

Role: lead