NCT05985720

Brief Summary

Evaluation of cardiac biomarkers and the left and right ventricular systolic and diastolic function in asthmatic children in Assuit university hospital

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Dec 2023

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 30, 2023

Completed
5 months until next milestone

First Posted

Study publicly available on registry

August 14, 2023

Completed
4 months until next milestone

Study Start

First participant enrolled

December 1, 2023

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2024

Completed
Last Updated

August 14, 2023

Status Verified

July 1, 2023

Enrollment Period

4 months

First QC Date

March 30, 2023

Last Update Submit

August 3, 2023

Conditions

Keywords

asthmacardiac affection

Outcome Measures

Primary Outcomes (2)

  • to identify the relation between asthmatic children and cardiac function

    relation between asthma and cardiac function

    Baseline

  • to identify the relation between asthmatic children and myocardial dysfunction

    relation between asthma and myocardial dysfunction

    Baseline

Other Outcomes (1)

  • to identify the relation between asthmatic children and child weight

    Baseline

Eligibility Criteria

Age5 Years - 15 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

children aged from 5 years to 15 years diagnosed as bronchial asthma

You may qualify if:

  • all pediatric cases between the age of 5 -15years with acute severe bronchial asthma who were admitted in pediatric emergency care unit

You may not qualify if:

  • Children with congenital or acquired heart diseases
  • Foreign body aspiration .
  • Chest infections
  • Tuberculosis or pneumonia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (5)

  • Rodriguez-Roisin R, Ballester E, Roca J, Torres A, Wagner PD. Mechanisms of hypoxemia in patients with status asthmaticus requiring mechanical ventilation. Am Rev Respir Dis. 1989 Mar;139(3):732-9. doi: 10.1164/ajrccm/139.3.732.

    PMID: 2923373BACKGROUND
  • Peng SM, Sun P, Zeng J, Deng XM. [Cardiac function of children with bronchial asthma]. Zhongguo Dang Dai Er Ke Za Zhi. 2006 Oct;8(5):388-90. Chinese.

    PMID: 17052399BACKGROUND
  • Zeybek C, Yalcin Y, Erdem A, Polat TB, Aktuglu-Zeybek AC, Bayoglu V, Akdeniz C, Celebi A. Tissue Doppler echocardiographic assessment of cardiac function in children with bronchial asthma. Pediatr Int. 2007 Dec;49(6):911-7. doi: 10.1111/j.1442-200X.2007.02486.x.

    PMID: 18045296BACKGROUND
  • Shedeed SA. Right ventricular function in children with bronchial asthma: a tissue Doppler echocardiographic study. Pediatr Cardiol. 2010 Oct;31(7):1008-15. doi: 10.1007/s00246-010-9753-2. Epub 2010 Aug 10.

    PMID: 20697704BACKGROUND
  • Sears MR. Trends in the prevalence of asthma. Chest. 2014 Feb;145(2):219-225. doi: 10.1378/chest.13-2059.

    PMID: 24493506BACKGROUND

MeSH Terms

Conditions

Ventricular DysfunctionAsthma

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesBronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

March 30, 2023

First Posted

August 14, 2023

Study Start

December 1, 2023

Primary Completion

April 1, 2024

Study Completion

April 1, 2024

Last Updated

August 14, 2023

Record last verified: 2023-07