Effect of a Daily Text Reminder on Asthma Medication Use, Symptom Control, and Lung Function in Children

NCT07053839 | Completed

• 2 other identifiers: 0726-2023-UPAO0422-2023-D-EPG-UPAO
• Study Type: interventional
• Target: 64
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to learn if a daily text reminder ("AdhasText") can help children with asthma use their inhalers regularly, control their symptoms, and improve their lung function. The main questions it aims to answer are: Does the daily text reminder improve adherence to inhaled corticosteroids in children with asthma? Does the text reminder help children with asthma control their symptoms better? Does the text reminder improve lung function in children with asthma? Researchers will compare children who receive the daily text reminder with usual care to children who receive usual care (without the reminder) to see if the text reminder improves adherence, symptom control, and lung function. Participants will: Receive a daily text reminder or usual care (no reminder) for 90 days Complete questionnaires about their asthma symptoms at 45 and 90 days Have spirometry tests to measure lung function at the start of the study and 90 days

Conditions

Asthma in Children

Keywords

Text message; asthma; treatment adherence; symptom control; spirometry; children

Outcome Measures

Primary Outcomes (1)

• Change in Inhaler Adherence as Measured by the Inhaler Adherence Scale for Children (IASC) at 45 and 90 Days

  Inhaler adherence was measured using the Inhaler Adherence Scale for Children (IASC), which evaluates adherence across three domains: Cognitive, Psychosocial, and Control \& Autonomy. The scale consists of 12 questions, with responses ranging from 0 (indicating poor adherence) to 4 (indicating full adherence) for each question. A higher total score indicates better adherence.

  45 days (T1) and 90 days (T2) after the intervention

Secondary Outcomes (2)

• Change in Asthma Symptom Control as Measured by the ACT (Asthma Control Test) and c-ACT (Childhood Asthma Control Test) at 45 and 90 Days

  Day 45 and day 90 after the intervention

• Change in Pulmonary Function as Measured by Spirometry at 90 Days

  Baseline and day 90 after the intervention

Study Arms (2)

Daily Text Reminder (AdhasText)

EXPERIMENTAL

Participants in this group will receive a daily text message reminder ("AdhasText") to encourage them to use their inhalers regularly for 90 days. They will continue with their regular asthma management as prescribed by their healthcare providers.

Behavioral: Daily Text Reminder

Usual care

NO INTERVENTION

Participants in this group will receive the usual care for asthma, which does not include the daily text message reminders. They will continue with their regular asthma management as prescribed by their healthcare providers.

Interventions

Daily Text Reminder BEHAVIORAL

The intervention, titled "AdhasText," involved sending a daily SMS reminder to caregivers, specifically mothers of children with asthma. The message, "If you want to stay healthy, you must use your inhaler," was sent at 7:00 p.m. over a 90 days period.

Daily Text Reminder (AdhasText)

Eligibility Criteria

• Age: 5 Years - 14 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Children aged 5 to 14 years with a clinical diagnosis of asthma
• Children who required initiation of treatment with a fixed and regular dose of inhaled corticosteroids
• Mothers or caregivers who had a mobile phone capable of sending and receiving text messages

You may not qualify if:

• Children with congenital heart disease
• Children who were unable to perform baseline spirometry
• Children who experienced at least one exacerbation during the pre-randomization period

Sponsors & Collaborators

• ROXANA AZNARAN TORRES: lead

Study Sites (1)

Hospital Regional Docente de Trujillo

Trujillo, La Libertad, 20230, Peru

Location

Related Publications (5)

• Jeminiwa R, Hohmann L, Qian J, Garza K, Hansen R, Fox BI. Impact of eHealth on medication adherence among patients with asthma: A systematic review and meta-analysis. Respir Med. 2019 Mar;149:59-68. doi: 10.1016/j.rmed.2019.02.011. Epub 2019 Feb 15.

  PMID: 30803887 BACKGROUND

• Chan AH, Stewart AW, Harrison J, Camargo CA Jr, Black PN, Mitchell EA. The effect of an electronic monitoring device with audiovisual reminder function on adherence to inhaled corticosteroids and school attendance in children with asthma: a randomised controlled trial. Lancet Respir Med. 2015 Mar;3(3):210-9. doi: 10.1016/S2213-2600(15)00008-9. Epub 2015 Jan 21.

  PMID: 25617215 BACKGROUND

• Quanjer PH, Stanojevic S, Cole TJ, Baur X, Hall GL, Culver BH, Enright PL, Hankinson JL, Ip MS, Zheng J, Stocks J; ERS Global Lung Function Initiative. Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations. Eur Respir J. 2012 Dec;40(6):1324-43. doi: 10.1183/09031936.00080312. Epub 2012 Jun 27.

  PMID: 22743675 BACKGROUND

• Morton RW, Everard ML, Elphick HE. Adherence in childhood asthma: the elephant in the room. Arch Dis Child. 2014 Oct;99(10):949-53. doi: 10.1136/archdischild-2014-306243. Epub 2014 May 29.

  PMID: 24876303 BACKGROUND

• Papi A, Brightling C, Pedersen SE, Reddel HK. Asthma. Lancet. 2018 Feb 24;391(10122):783-800. doi: 10.1016/S0140-6736(17)33311-1. Epub 2017 Dec 19.

  PMID: 29273246 BACKGROUND

MeSH Terms

Conditions

Asthma; Treatment Adherence and Compliance

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases; Health Behavior; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal investigator, MD, PhD

Study Record Dates

• First Submitted: June 27, 2025
• First Posted: July 8, 2025
• Study Start: July 22, 2023
• Primary Completion: September 30, 2024
• Study Completion: September 30, 2024
• Last Updated: July 8, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

PE (1)