Sleep & Stress in Healthcare Providers After Defined Music Intervention Measure by 7-Tesla fMRI & Actigraphy

NCT05980429 | Completed

• 1 other identifier: PRO00024163
• Study Type: interventional
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

This study plans to explore whether specially chosen relaxing music can help improve sleep, reduce stress, and prevent burnout in healthcare workers, many of whom are often sleep-deprived. The researchers will measure changes in brain activity, sleep patterns, and self-reported stress levels before, during, and after participants listen to this music. The novel approach includes using advanced brain scanning technology, sleep monitoring devices, and carefully selected music. Ultimately, the aim is to create a scientifically backed music intervention that can be used widely to help healthcare providers get better sleep and manage stress, potentially reducing burnout rates.

Conditions

Stress, Psychological; Burnout, Professional; Sleep Deprivation; Music Therapy

Keywords

Stress; Burnout; fMRI; Sleep; Deprivation; Music; Therapy

Outcome Measures

Primary Outcomes (3)

• Mean change in quantity of sleep (total sleep duration, hours)

  Hours of sleep recorded by the WHOOP device pre to post intervention

  6 weeks

• Mean change in quality of sleep (light sleep duration, hours)

  Hours of light sleep recorded by the WHOOP device pre to post intervention

  6 weeks

• Mean change in quality of sleep (rapid eye movement sleep duration, hours)

  Hours of rapid eye movement sleep recorded by the WHOOP device pre to post intervention

  6 weeks

Secondary Outcomes (4)

• Mean change in resting heart rate, beats per minute

  6 weeks

• Mean change in heart rate variability root mean square of successive rate rhythm interval differences

  6 weeks

• Mean change in response to Intensive Care Unit noise

  6 weeks

• Mean change in empathetic response

  6 weeks

Study Arms (3)

Music Therapy, Prescribed

EXPERIMENTAL

During weeks 2-5, participants in the prescribed music group underwent a minimum of 15 minutes (mandatory) of nightly self-administered music intervention immediately before bedtime.

Other: Music Therapy, prescribed

Music Therapy, Self-selected

EXPERIMENTAL

During weeks 2-5, participants in the self-selected music group underwent a minimum of 15 minutes (mandatory) of nightly self-administered music intervention immediately before bedtime.

Other: Music Therapy, self-selected

No Music Therapy Control

NO INTERVENTION

During weeks 2-5, participants in the no-music group continued as usual.

Interventions

Music Therapy, prescribed OTHER

All music pieces selected for the prescribed intervention contain compositional elements of relaxation analyzed, prepared, and recorded by professional concert artists and a Grammy-nominated composer. The compositional elements included Accentuation, Articulation, Dynamic Range, Familiarity, Interpretive Expertise, Melodic Shape, Meter, Recording Quality, Repetition, Register, Rubato, Tempo, Texture, Timbre, Transition, and Tonality. These 15 repertoire-selecting parameters were used to choose the prescribed music play list for this study. Music used for the study was downloaded from a password-protected Google Drive accessible to the study participants assigned to the "prescribed music" intervention group.

Music Therapy, Prescribed

Music Therapy, self-selected OTHER

All music pieces were self-selected by the participant

Music Therapy, Self-selected

Eligibility Criteria

• Age: 30 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• attending surgeon at Houston Methodist Hospital, Houston, Texas

You may not qualify if:

• diagnosed sleep apnea
• hearing impairment
• cognitive impairment
• large metal implants
• Self-reported regular use of prescribed sleep medications

Sponsors & Collaborators

• The Methodist Hospital Research Institute: lead

Study Sites (1)

Houston Methodist Hospital

Houston, Texas, 77030, United States

Location

Related Publications (10)

• McPherson T, Berger D, Alagapan S, Frohlich F. Active and Passive Rhythmic Music Therapy Interventions Differentially Modulate Sympathetic Autonomic Nervous System Activity. J Music Ther. 2019 Aug 13;56(3):240-264. doi: 10.1093/jmt/thz007.

  PMID: 31175814 BACKGROUND

• Shaffer F, Ginsberg JP. An Overview of Heart Rate Variability Metrics and Norms. Front Public Health. 2017 Sep 28;5:258. doi: 10.3389/fpubh.2017.00258. eCollection 2017.

  PMID: 29034226 BACKGROUND

• Nowak J, Dimitrov A, Oei NYL, Walter H, Adli M, Veer IM. Association of naturally occurring sleep loss with reduced amygdala resting-state functional connectivity following psychosocial stress. Psychoneuroendocrinology. 2020 Apr;114:104585. doi: 10.1016/j.psyneuen.2020.104585. Epub 2020 Jan 24.

  PMID: 32018119 BACKGROUND

• Strine TW, Chapman DP. Associations of frequent sleep insufficiency with health-related quality of life and health behaviors. Sleep Med. 2005 Jan;6(1):23-7. doi: 10.1016/j.sleep.2004.06.003.

  PMID: 15680291 BACKGROUND

• Oskrochi Y, Maruthappu M, Henriksson M, Davies AH, Shalhoub J. Beyond the body: A systematic review of the nonphysical effects of a surgical career. Surgery. 2016 Feb;159(2):650-64. doi: 10.1016/j.surg.2015.08.017. Epub 2015 Oct 1.

  PMID: 26431813 BACKGROUND

• Dyrbye LN, West CP, Satele D, Boone S, Tan L, Sloan J, Shanafelt TD. Burnout among U.S. medical students, residents, and early career physicians relative to the general U.S. population. Acad Med. 2014 Mar;89(3):443-51. doi: 10.1097/ACM.0000000000000134.

  PMID: 24448053 BACKGROUND

• Shanafelt TD, Boone S, Tan L, Dyrbye LN, Sotile W, Satele D, West CP, Sloan J, Oreskovich MR. Burnout and satisfaction with work-life balance among US physicians relative to the general US population. Arch Intern Med. 2012 Oct 8;172(18):1377-85. doi: 10.1001/archinternmed.2012.3199.

  PMID: 22911330 BACKGROUND

• Deneva T, Ianakiev Y, Keskinova D. Burnout Syndrome in Physicians-Psychological Assessment and Biomarker Research. Medicina (Kaunas). 2019 May 24;55(5):209. doi: 10.3390/medicina55050209.

  PMID: 31137738 BACKGROUND

• Jackson-Koku G, Grime P. Emotion regulation and burnout in doctors: a systematic review. Occup Med (Lond). 2019 Feb 7;69(1):9-21. doi: 10.1093/occmed/kqz004.

  PMID: 30753715 BACKGROUND

• Zentner M, Grandjean D, Scherer KR. Emotions evoked by the sound of music: characterization, classification, and measurement. Emotion. 2008 Aug;8(4):494-521. doi: 10.1037/1528-3542.8.4.494.

  PMID: 18729581 BACKGROUND

MeSH Terms

Conditions

Stress, Psychological; Burnout, Professional; Sleep Deprivation; Burnout, Psychological

Interventions

Music Therapy

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior; Occupational Stress; Occupational Diseases; Dyssomnias; Sleep Wake Disorders; Nervous System Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Mental Disorders

Intervention Hierarchy (Ancestors)

Sensory Art Therapies; Complementary Therapies; Therapeutics; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Psychotherapy; Behavioral Disciplines and Activities

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Clinical Medicine in Clinical Surgery

Model Details: Participants were enrolled from the surgery staff at a quaternary care hospital after signing informed consent and were randomized using block randomization (1:1:1) to one of 3 groups: (1) 30 minutes of prescribed musical intervention at bedtime (PM), (2) 30 minutes of self-selected music listening at bedtime (PS), or (3) unaltered, normal bedtime routine, as a control (C).

Study Record Dates

• First Submitted: July 18, 2023
• First Posted: August 8, 2023
• Study Start: June 1, 2020
• Primary Completion: June 30, 2021
• Study Completion: August 31, 2021
• Last Updated: March 15, 2024

Record last verified: 2024-03

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)