Thigh Muscle Mass and Muscle Wasting in Patients in the Emergency Department

NCT05978154 | Unknown

• 1 other identifier: musclemassandwastingined
• Study Type: observational
• Target: 600
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to evaluate whether thigh muscle mass and muscle wasting are associated with mortality in patients who visit the emergency department. The main questions it aims to answer are:

• Is thigh muscle mass associated with mortality in patient who visit the emergency department?
• Does muscle wasting exist during staying in the emergency department?
• Is muscle wasting associated with mortality in patient who visit the emergency department? Participants will be evaluated for serial thigh muscle mass using point-of-care ultrasound at the emergency department.

Conditions

Sepsis; Cardiac Arrest; Acute Respiratory Failure; Patients Who Visit Emergency Department; Shock; Trauma

Outcome Measures

Primary Outcomes (1)

• 28 day mortality

  28 day mortality

  28 days after study enrollment

Interventions

Thigh muscle mass and muscle wasting (exposure) OTHER

Thigh muscle mass and muscle wasting (exposure variable)

Eligibility Criteria

• Age: 19 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients who visit the emergency department with informed consent and then who undergo point-of-care ultrasound to evaluate thigh muscle mass.

You may qualify if:

• patients who visit the emergency department of Korea University Ansan Hospital during study period
• patients with age within the limits
• patients who are willing to be participate the study with informed consent
• patients who undergo point-of-care ultrasound to evaluate thigh muscle mass

You may not qualify if:

• patients with age out of limits
• patients who have deformities on lower leg
• patients who is unable to maintain appropriate position to undergo point-of-care ultrasound
• patients who decline to participate the study
• patients who have 'do-not-resuscitate' order or are not willing to be resuscitated
• patients of whom point-of-care ultrasound on thigh muscle mass was not performed

Sponsors & Collaborators

• Korea University Ansan Hospital: lead

Study Sites (1)

Korea University Ansan Hospital

Ansan-si, Gyeonggi-do, 15355, South Korea

RECRUITING

MeSH Terms

Conditions

Sepsis; Heart Arrest; Shock; Wounds and Injuries

Condition Hierarchy (Ancestors)

Infections; Systemic Inflammatory Response Syndrome; Inflammation; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Heart Diseases; Cardiovascular Diseases

Central Study Contacts

Sejoong Ahn

CONTACT

82-10-2946-0250; sejongahn@naver.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Korea University Ansan Hospital

Study Record Dates

• First Submitted: July 28, 2023
• First Posted: August 7, 2023
• Study Start: July 28, 2023
• Primary Completion: December 31, 2024
• Study Completion: March 31, 2025
• Last Updated: August 7, 2023

Record last verified: 2023-07

Data Sharing

• IPD Sharing: Will not share

Locations

KR (1)