Study of the Characteristics of Chronic Pain in Patients With Addiction

NCT05976178 | Completed

• 1 other identifier: 56LORC_2021_ADDICTALGO
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

It is described in the literature a higher prevalence of pain in patients with an addiction but there are few studies describing the pain profile of patients with use disorder. Pain has a very negative impact on the quality of life of opioid substituted patients. Improving knowledge on this point would make it possible to better guide specific care. The investigator proposes to conduct a single-center descriptive observational study using questionnaires, without changing the management of patients with chronic pain. The primary objective of the study is to determine the prevalence of chronic pain in patients with substance addiction hospitalized for addiction treatment.

Conditions

Chronic Pain; Addiction

Outcome Measures

Primary Outcomes (1)

• Prevalence of chronic pain in patients with substance addiction hospitalized for addiction treatment.

  Percentage of patients presenting with pain for more than three months among patients hospitalized in an addiction service for the management of an addiction

  During the hospitalization, maximum 1 month

Secondary Outcomes (8)

• Pain intensity in the last 24 hours

  During the hospitalization, maximum 1 month

• Interference of pain on the quality of life

  During the hospitalization, maximum 1 month

• Localisation of pain

  During the hospitalization, maximum 1 month

• Describe the frequency of the two main psychiatric comorbidities of chronic pain: anxiety

  During the hospitalization, maximum 1 month

• Describe the frequency of the two main psychiatric comorbidities of chronic pain: depression

  During the hospitalization, maximum 1 month

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients hospitalized in the addictology department of LORIENT Hospital, in full hospitalization or in a day hospital

You may qualify if:

• \> 18 years old
• Presence of addiction to at least one substance, based on DSM-5 criteria
• Hospitalized in the addiction service of LORIENT Hospital
• Knowing how to read and write French
• Not objecting to their participation in the study after informed information

You may not qualify if:

• Already included during a precedent hospitalization
• Adults subject to legal protection or deprived of their liberty.

Sponsors & Collaborators

• Groupe Hospitalier de Bretagne Sud: lead

Study Sites (1)

Groupe Hospitalier Bretagne Sud

Lorient, 56100, France

Location

Related Publications (5)

• Rosenblum A, Joseph H, Fong C, Kipnis S, Cleland C, Portenoy RK. Prevalence and characteristics of chronic pain among chemically dependent patients in methadone maintenance and residential treatment facilities. JAMA. 2003 May 14;289(18):2370-8. doi: 10.1001/jama.289.18.2370.

  PMID: 12746360 BACKGROUND

• Lusted A, Roerecke M, Goldner E, Rehm J, Fischer B. Prevalence of pain among nonmedical prescription opioid users in substance use treatment populations: systematic review and meta-analyses. Pain Physician. 2013 Nov-Dec;16(6):E671-84.

  PMID: 24284850 BACKGROUND

• Breivik H, Collett B, Ventafridda V, Cohen R, Gallacher D. Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment. Eur J Pain. 2006 May;10(4):287-333. doi: 10.1016/j.ejpain.2005.06.009. Epub 2005 Aug 10.

  PMID: 16095934 BACKGROUND

• Voon P, Greer AM, Amlani A, Newman C, Burmeister C, Buxton JA. Pain as a risk factor for substance use: a qualitative study of people who use drugs in British Columbia, Canada. Harm Reduct J. 2018 Jul 5;15(1):35. doi: 10.1186/s12954-018-0241-y.

  PMID: 29976203 BACKGROUND

• Larson MJ, Paasche-Orlow M, Cheng DM, Lloyd-Travaglini C, Saitz R, Samet JH. Persistent pain is associated with substance use after detoxification: a prospective cohort analysis. Addiction. 2007 May;102(5):752-60. doi: 10.1111/j.1360-0443.2007.01759.x.

  PMID: 17506152 BACKGROUND

MeSH Terms

Conditions

Chronic Pain; Behavior, Addictive

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Compulsive Behavior; Impulsive Behavior; Behavior

Study Officials

• Alexandre Cauchie, MD

  GH Bretagne Sud

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 11, 2023
• First Posted: August 4, 2023
• Study Start: December 10, 2022
• Primary Completion: March 1, 2025
• Study Completion: March 1, 2025
• Last Updated: May 11, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)