Refining the Interpretation of the Tinel's Sign for Carpal Tunnel Syndrome

NCT05969093 | Unknown

• 1 other identifier: 012/TINEL2023
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This is an observational study to investigate the electromyographic (EMG) activity and nerve conduction velocity (NCV) of healthy individuals during the Tinel's Sign performed at different wrist positions. The study aims to identify the wrist position that best isolates median nerve activity during the Tinel's Sign.

Conditions

Carpal Tunnel Syndrome

Outcome Measures

Primary Outcomes (4)

• EMG activity of the thenar muscles during the Tinel's Sign performed at different wrist positions.

  The amplitude of EMG activity of the thenar muscles will be measured during the Tinel's Sign performed at different wrist positions. The amplitude will be quantified in microvolts (µV).

  Baseline

• EMG activity of the hypothenar muscles during the Tinel's Sign performed at different wrist positions.

  The amplitude of EMG activity of the hypothenar muscles will be measured during the Tinel's Sign performed at different wrist positions. The amplitude will be quantified in microvolts (µV).

  Baseline

• Nerve conduction velocity of the median nerve during the Tinel's Sign performed at different wrist positions.

  The NCV of the median nerve will be measured during the Tinel's Sign performed at different wrist positions. The NCV will be quantified in meters per second (m/s).

  Baseline

• Nerve conduction velocity of the ulnar nerve during the Tinel's Sign performed at different wrist positions.

  The NCV of the ulnar nerve will be measured during the Tinel's Sign performed at different wrist positions. The NCV will be quantified in meters per second (m/s).

  Baseline

Study Arms (1)

Healthy individuals

Participants will undergo the Tinel's Sign at different wrist positions while EMG activity and NCV are recorded.

Diagnostic Test: Tinel's Sign performed at different wrist positions

Interventions

Tinel's Sign performed at different wrist positions DIAGNOSTIC_TEST

Participants will undergo the Tinel's Sign at different wrist positions while EMG activity and NCV are recorded to investigate the effect of wrist position on median nerve activity.

Healthy individuals

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Healthy individuals aged 18-60 years

You may qualify if:

• Healthy individuals aged 18-45 years
• No history of hand or wrist pain, neurological or muscular disorders

You may not qualify if:

• Any contraindications to EMG or NCV measurement

Sponsors & Collaborators

• Ahram Canadian University: lead

Study Sites (1)

Outpatient clinic of faculty of physical therapy, Ahram Canadian University

Al Ḩayy Ath Thāmin, Giza Governorate, 3221405, Egypt

RECRUITING

MeSH Terms

Conditions

Carpal Tunnel Syndrome

Condition Hierarchy (Ancestors)

Median Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries

Study Officials

• Amal Fawzy, Ph.d

  Faculty of Physical Therapy, Ahram Canadian University

  STUDY CHAIR

Central Study Contacts

Mohamed M ElMeligie, Ph.d

CONTACT

+201064442032; mohamed.elmeligie@acu.edu.eg

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Physical Therapy and Director of Electromyography Lab

Study Record Dates

• First Submitted: July 22, 2023
• First Posted: August 1, 2023
• Study Start: July 29, 2023
• Primary Completion: December 23, 2023
• Study Completion: January 1, 2024
• Last Updated: August 1, 2023

Record last verified: 2023-07

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)