NCT05961163

Brief Summary

The CLIMATE Observational Study examines to what extent chronically ill patients experience adverse health effects because of heat and whether the patients' specific efforts, somatosensory amplification, self-efficacy, health literacy and commitment to the GP, degree of urbanisation of the patients' administration district and characteristics of the patients' neighborhood are associated with these effects.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
61

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jul 2023

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 17, 2023

Completed
7 days until next milestone

Study Start

First participant enrolled

July 24, 2023

Completed
3 days until next milestone

First Posted

Study publicly available on registry

July 27, 2023

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 3, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 3, 2023

Completed
Last Updated

September 13, 2023

Status Verified

September 1, 2023

Enrollment Period

1 month

First QC Date

July 17, 2023

Last Update Submit

September 8, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Composite index of nausea, vomiting, tiredness/fatigue, vertigo, circulation problems/syncopes, muscle cramps, headache, extrasystoles, palpitations, edemas, shortness of breath, depressive mood, anxiety, mental confusion

    The severity in each symptom category is defined by the degree of limitations in usual activities. The composite index expresses the highest severity within any symptom category.

    Once per week between 29 July - 27 October 2023

Secondary Outcomes (3)

  • Self-rated health

    Once per week between 29 July - 27 October 2023

  • Use of medical services

    Once per week between 29 July - 27 October 2023

  • Reasons for drop out (eg, bad health condition, hospital admission, death)

    Once after 27 October 2023

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The study is located in different sites in Germany. Patients from approximately 50 GP practices will be included. In each practice, eligible patients receive a flyer including a QR-Code and a short link to register for the online study. After documenting informed consent within the application, patients fill out the baseline questionnaire and receive invitations for twelve subsequent assessments of symptoms by email. The investigators estimated that approximately 1500 patients will be contacted. From experience with similar studies the investigators anticipated a response rate of 40% (=600 patients).

You may qualify if:

  • being 18 years or older
  • at least one of the following conditions: Coronary Heart Disease; Myocardial Infarction; Heart Failure (NYHA stage II or higher); Cardiac Arrhythmias (treated with medication); Peripheral Artery Disease (Fontaine-Ratschow stage II or higher); Stroke; Transient Ischemic Attack; Diabetes Mellitus (Type 1 or 2 treated with oral medication or insulin); Chronic Obstructive Pulmonary Disease (GOLD stage 2 or higher); Asthma (GINA stage II or higher); Renal Insufficiency (KDIGO stage III or higher), Depressive Disorder (treated with medication); Anxiety Disorders (treated with medication), Schizophrenia (treated with medication); Peripheral Nervous System Diseases (with regularly or persistently occurring symptoms).

You may not qualify if:

  • no capacity to consent
  • severe visual impairment
  • insufficient German language skills
  • not able to use internet browser (eg, lack of hardware)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universitätsklinikum Hamburg-Eppendorf

Hamburg, Germany

Location

Related Publications (1)

  • Jordan A, Nothacker J, Paucke V, Hager KH, Hueber S, Karimzadeh A, Kotter T, Loffler C, Muller BS, Tajdar D, Luhmann D, Scherer M, Schafer I. Association Between Self-Reported Protective Behavior and Heat-Associated Health Complaints Among Patients With Chronic Diseases in Primary Care: Results of the CLIMATE Pilot Cohort Study. JMIR Public Health Surveill. 2024 Nov 4;10:e58711. doi: 10.2196/58711.

MeSH Terms

Conditions

Coronary DiseaseMyocardial InfarctionHeart FailureArrhythmias, CardiacPeripheral Arterial DiseaseStrokeIschemic Attack, TransientDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Pulmonary Disease, Chronic ObstructiveAsthmaRenal InsufficiencyDepressive DisorderAnxiety DisordersSchizophreniaPeripheral Nervous System Diseases

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosisAtherosclerosisArteriosclerosisArterial Occlusive DiseasesPeripheral Vascular DiseasesCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesBrain IschemiaDiabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAutoimmune DiseasesImmune System DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesBronchial DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesMood DisordersMental DisordersSchizophrenia Spectrum and Other Psychotic DisordersNeuromuscular Diseases

Study Officials

  • Ingmar Schäfer, PD Dr.

    Universitätsklinikum Hamburg-Eppendorf

    PRINCIPAL INVESTIGATOR
  • Martin Scherer, Prof. Dr.

    Universitätsklinikum Hamburg-Eppendorf

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 17, 2023

First Posted

July 27, 2023

Study Start

July 24, 2023

Primary Completion

September 3, 2023

Study Completion

September 3, 2023

Last Updated

September 13, 2023

Record last verified: 2023-09

Data Sharing

IPD Sharing
Will not share

IPD will be available from the corresponding authors of study publications upon reasonable request.

Locations