NCT05950620

Brief Summary

This project aims to move what is currently a specialty-care model for the management of obesity of children and adolescents into the primary care setting.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
400

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2022

Longer than P75 for all trials

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2022

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

July 11, 2023

Completed
7 days until next milestone

First Posted

Study publicly available on registry

July 18, 2023

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2026

Completed
Last Updated

July 19, 2023

Status Verified

July 1, 2023

Enrollment Period

4 years

First QC Date

July 11, 2023

Last Update Submit

July 17, 2023

Conditions

Outcome Measures

Primary Outcomes (6)

  • Change in body weight

    Body weight in kg

    Baseline to follow-up (1-3 years)

  • Change in body height

    Body height in meters

    Baseline to follow-up (1-3 years)

  • Change in BMI

    BMI will be calculated using the formula: kg weight / m2 height. Will be in both absolute and percentile for age

    Baseline to follow-up (1-3 years)

  • Impact on glucose control

    Hemoglobin A1c levels

    Baseline to follow-up (1-3 years)

  • Impact on fatty liver

    Levels of liver enzymes ALT, AST

    Baseline to follow-up (1-3 years)

  • Impact on lipid levels

    Levels of total, LDL, HDL, and non-HDL cholesterol. Triglycerides.

    Baseline to follow-up (1-3 years)

Secondary Outcomes (1)

  • Patient follow-up metrics

    Baseline to follow-up (1-3 years)

Study Arms (2)

Intervention

Pediatric patients with obesity or in need of weight management for unwanted weight gain.

Other: Medical obesity management.

Controls

Historic controls matched to the Intervention group on age, sex, and BMI percentile.

Interventions

Dietician visits, education, anti-obesity medications, and/or referral for metabolic-bariatric surgery as indicated by American Academy of Pediatrics guidelines for obesity management.

Intervention

Eligibility Criteria

Age1 Month - 21 Years
Sexall
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Patients in a general pediatrician's office internally in Portland, Oregon.

You may qualify if:

  • Children with obesity (BMI \> 30 kg/m2 or \> 95th percentile) or in need of weight management of unwanted weight gain.

You may not qualify if:

  • None.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

The Children's Clinic

Portland, Oregon, 97225, United States

RECRUITING

Oregon Health & Science University

Portland, Oregon, 97239, United States

ACTIVE NOT RECRUITING

MeSH Terms

Conditions

Pediatric Obesity

Condition Hierarchy (Ancestors)

ObesityOverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Jonathan Q Purnell, MD

CONTACT

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

July 11, 2023

First Posted

July 18, 2023

Study Start

July 1, 2022

Primary Completion

June 30, 2026

Study Completion

June 30, 2026

Last Updated

July 19, 2023

Record last verified: 2023-07

Data Sharing

IPD Sharing
Will not share

This study uses anonymized data. No IPD will be generated.

Locations