NCT05922943

Brief Summary

This community-based study will assess the efficacy of a culturally adapted, yoga-based intervention to reduce sitting time, increase physical activity, and improve psychosocial wellbeing among insufficiently active Black adults in the Houston area.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
250

participants targeted

Target at P75+ for not_applicable

Timeline
38mo left

Started Aug 2024

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress35%
Aug 2024Jun 2029

First Submitted

Initial submission to the registry

June 20, 2023

Completed
8 days until next milestone

First Posted

Study publicly available on registry

June 28, 2023

Completed
1.1 years until next milestone

Study Start

First participant enrolled

August 14, 2024

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2027

Expected
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2029

Last Updated

October 23, 2025

Status Verified

October 1, 2025

Enrollment Period

2.9 years

First QC Date

June 20, 2023

Last Update Submit

October 21, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Quality of life questionnaires

    through study completion; an average of 6 months

Study Arms (1)

Harmony & Health program

EXPERIMENTAL

Participants will take part in the Harmony \& Health program or participants will attend in-person group health education sessions 2 times a week for 8 weeks.

Behavioral: Harmony & Health program

Interventions

Harmony \& Health program may help improve psychosocial wellbeing in participants and if improvements in physical activity and wellbeing can last after the program ends. Yoga combines gentle movements, breathing exercises, relaxation techniques, and meditation all tailored to the participant's needs.

Harmony & Health program

Eligibility Criteria

Age18 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Adults ≥18 years old
  • Self-identify as Black or African American
  • Self-reports MVPA \<150 minutes/week
  • Self-reports sedentary time ≥6 hours/ day
  • Body mass index \[BMI\] ≥25.0 kg/m2 based on self-reported height and weight (and verified at baseline)
  • Able to pass the modified Physical Activity Readiness Questionnaire (PAR-Q) or provide physician's clearance to participate
  • Willing to be randomized to intervention or control
  • Comfortable participating in group-based physical activity
  • Able to read, speak, and write in English
  • Able to provide written informed consent without assistance

You may not qualify if:

  • \< 18 years old
  • Self-reports MVPA .150 minutes/week
  • Self-reports sedentary time \<6 hours/day
  • Not classified as overweight or obese (BMI \<25.0 kg/m2)
  • Absolute contraindications to unassisted physical activity (e.g. acute MI, orthopedic and musculoskeletal limitations)
  • Practicing yoga or enrolled in another program targeting physical activity, sedentary behavior, or weight loss in the last 6 months
  • Previously participated in Harmony \& Health
  • Pregnant or planning to become pregnant in the next 6 months
  • Planning to move from the Houston area within the next 6 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

M D Anderson Cancer Center

Houston, Texas, 77030, United States

RECRUITING

Related Links

Study Officials

  • Scherezade Mama, DRPH

    M.D. Anderson Cancer Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Scherezade Mama, DRPH

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 20, 2023

First Posted

June 28, 2023

Study Start

August 14, 2024

Primary Completion (Estimated)

June 30, 2027

Study Completion (Estimated)

June 30, 2029

Last Updated

October 23, 2025

Record last verified: 2025-10

Locations