NCT05918146

Brief Summary

Physical therapy and hypertonic dextrose prolotherapy are often used to treat subdeltoid bursitis. This study aims to investigate the effects of hypertonic dextrose injection on physical therapy through a double-blind, randomized study.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
46

participants targeted

Target at P25-P50 for phase_4

Timeline
Completed

Started Jun 2023

Shorter than P25 for phase_4

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 15, 2023

Completed
5 days until next milestone

Study Start

First participant enrolled

June 20, 2023

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 26, 2023

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2024

Completed
Last Updated

June 27, 2023

Status Verified

June 1, 2023

Enrollment Period

1 year

First QC Date

June 15, 2023

Last Update Submit

June 23, 2023

Conditions

Keywords

subdeltoid bursitisdextrosephysical therapy

Outcome Measures

Primary Outcomes (1)

  • Shoulder pain and disability index

    measure shoulder pain and disability, ranges from 0-100, higher scores indicate more pain or disability

    score change from baseline to 1 week, 1 month and 3 months after treatment

Secondary Outcomes (3)

  • Disabilities of the arm, shoulder, and hand

    score change from baseline to 1 week, 1 month and 3 months after treatment

  • Visual analog scale

    score change from baseline to 1 week, 1 month and 3 months after treatment

  • range of motion

    score change from baseline to 1 week, 1 month and 3 months after treatment

Study Arms (2)

Intervention group

EXPERIMENTAL

Dextrose injection, one time

Drug: Dextrose

Control group

PLACEBO COMPARATOR

Normal saline injection, one time

Drug: Normal saline

Interventions

Dextrose injection plus physical therapy

Also known as: physical therapy
Intervention group

Normal saline injection plus physical therapy

Also known as: physical therapy
Control group

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • clinical diagnosis of subdeltoid bursitis age 20 or older 20 at least one positive in the painful arc, neer test, or Hawkins test can attend 3 months of intervention and follow up

You may not qualify if:

  • history of malignancy previous shoulder operation or injury previous shoulder injections in the past 3 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shin Kong Wu Ho-Su Memorial Hospital

Taipei, 111-01, Taiwan

Location

MeSH Terms

Interventions

GlucosePhysical Therapy ModalitiesSaline Solution

Intervention Hierarchy (Ancestors)

HexosesMonosaccharidesSugarsCarbohydratesTherapeuticsRehabilitationCrystalloid SolutionsIsotonic SolutionsSolutionsPharmaceutical Preparations

Study Officials

  • Ru-Lan Hsieh, MD

    Shin Kong Wu Ho-Su Memorial Hospital

    STUDY CHAIR

Central Study Contacts

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, Professor

Study Record Dates

First Submitted

June 15, 2023

First Posted

June 26, 2023

Study Start

June 20, 2023

Primary Completion

June 30, 2024

Study Completion

June 30, 2024

Last Updated

June 27, 2023

Record last verified: 2023-06

Data Sharing

IPD Sharing
Will not share

Locations