Investigation of Preoperative Frailty in Elderly Patients With Colorectal Cancer and Correlation Between Preoperative Frailty and Early Postoperative Prognosis

NCT05915637 | Completed

• 1 other identifier: KLLY-2021-025
• Study Type: observational
• Target: 336
• Locations: 1 country
• Sites: 1

Brief Summary

To investigate and analyze the status of preoperative frailty and its influencing factors in elderly patients with colorectal cancer using FRALL scale and other related scales, and to explore the correlation between preoperative frailty and early prognosis in elderly patients with colorectal cancer, so as to attract the attention of medical staff to preoperative frailty in this population and provide a preliminary research basis for the study of frailty intervention in these patients.

Conditions

Colorectal Cancer

Outcome Measures

Primary Outcomes (1)

• Fatigue Assessment

  Status of frailty will be assessed by FRALL Scale

  7 days

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Colorectal cancer was diagnosed according to the Chinese Guidelines for Diagnosis and Treatment of Colorectal Cancer (2020 edition) and planned to undergo elective laparoscopic radical resection of colorectal cancer

You may qualify if:

• age ≥60 years old;
• Colorectal cancer was diagnosed according to the Chinese Guidelines for Diagnosis and Treatment of Colorectal Cancer (2020 edition) and planned to undergo elective laparoscopic radical resection of colorectal cancer;
• able to complete physical assessment without communication barriers;
• voluntarily participated in this study after informed consent.

You may not qualify if:

• taking antidepressants, levodopa, donepezil hydrochloride and other drugs;
• patients with preoperative colorectal cancer surgery or neoadjuvant therapy;
• patients with TNM stage Ⅳ;
• complicated with other malignant tumors except primary skin cancer or melanoma.

Sponsors & Collaborators

• Zunyi Medical College: lead

Study Sites (1)

Yongmei Zhang

Zunyi, Guizhou, 563000, China

Location

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Study Director

Study Record Dates

• First Submitted: June 1, 2023
• First Posted: June 23, 2023
• Study Start: September 1, 2021
• Primary Completion: November 1, 2022
• Study Completion: November 1, 2022
• Last Updated: June 23, 2023

Record last verified: 2023-06

Locations

CN (1)