Establishment and Clinical Validation of New Technologies for Accurate Screening of Colorectal Cancer Based on Multi-omics
Research on New Technologies for Screening and Early Diagnosis of Malignant Tumors - Establishment and Clinical Validation of New Technologies for Accurate Screening of Colorectal Cancer Based on Multi-omics
1 other identifier
observational
9,000
1 country
3
Brief Summary
Background: The current screening techniques for colorectal cancer include colonoscopy, fecal occult blood, and high-risk factor questionnaires. However, the colorectal cancer screening technology that has been widely used at present cannot take into account sensitivity and specificity, and the tumor detection rate is low. The purpose of research:
- 1.Build a new type of population colorectal cancer precision screening technology program;
- 2.Improve the detection rate of colorectal cancer in the population by new methods (compared with the existing domestic advanced technology) by ≥20%, and improve the specificity of colorectal cancer screening by ≥15% without significantly reducing the sensitivity.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jul 2021
Typical duration for all trials
3 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 30, 2021
CompletedFirst Posted
Study publicly available on registry
June 4, 2021
CompletedStudy Start
First participant enrolled
July 1, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2024
CompletedJune 4, 2021
May 1, 2021
2.9 years
May 30, 2021
May 30, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Colorectal cancer detection rate in the population
Colorectal cancer detection rate in the population
through study completion, an average of 3 years
Colorectal cancer screening specificity
Colorectal cancer screening specificity
through study completion, an average of 3 years
Colorectal cancer screening sensitivity
Colorectal cancer screening sensitivity
through study completion, an average of 3 years
Eligibility Criteria
Individuals of 40-74 years old in non-high incidence of colorectal cancer areas(hospital outpatient population, community population in non-high-risk areas) .
You may qualify if:
- Age: 40-74 years old
You may not qualify if:
- Combine severe disorders to make it unsuitable for colonoscopy
- Combine other tumors
- Mental and behavioral abnormalities do not cooperate with the screener
- Researchers believe that other reasons are not suitable for enrollment
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (3)
Chinese Medicine Hospital of Haining City, Haining Cancer Preventional and Treatment Research Institute
Haining, Zhejiang, 314400, China
Jiashan County Cancer Prevention and Treatment Institute
Jiashan, Zhejiang, 314100, China
Lanxi City People's Hospital, Linjiang Hospital
Lanxi, Zhejiang, 321100, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- ECOLOGIC OR COMMUNITY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 30, 2021
First Posted
June 4, 2021
Study Start
July 1, 2021
Primary Completion
June 1, 2024
Study Completion
November 1, 2024
Last Updated
June 4, 2021
Record last verified: 2021-05