Development and Validation of a Risk Prediction Model for Preoperative Frailty in Elderly Patients With Colorectal Cancer

NCT05879861 | Unknown

• 1 other identifier: ZSKHZ Zi (2022) no. 337
• Study Type: observational
• Target: 364
• Locations: 1 country
• Sites: 1

Brief Summary

Fried Scale and its related scales were used to analyze the status and risk factors of preoperative frailty in elderly patients with colorectal cancer. R software was used to construct a risk prediction model for preoperative frailty in elderly patients with colorectal cancer, and its validity and stability were verified in clinical practice.

Conditions

Colorectal Cancer

Outcome Measures

Primary Outcomes (1)

• Status of frailty

  Status of frailty will be assessed by Fried Scale

  1 day

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients who met the diagnostic criteria of colorectal cancer in Chinese Guidelines for Diagnosis and Treatment of Colorectal Cancer 2020 Edition and underwent surgery.

You may qualify if:

• patients who met the diagnostic criteria of colorectal cancer in Chinese Guidelines for Diagnosis and Treatment of Colorectal Cancer 2020 Edition and underwent surgery;
• patients aged ≥60 years old ;
• patients who are clearly conscious, able to understand instructions, communicate normally, and complete the physical activity ability test without the assistance of others;
• patients who gave informed consent and volunteered to participate in the study.

You may not qualify if:

• patients with limb joint disease and lower limb pain;
• patients with serious heart, liver, kidney diseases could not complete the test;
• patients with visual impairment and hearing impairment;
• patients with a history of mental illness or drug dependence;
• taking antidepressants, levodopa/carbidopa, donepezil hydrochloride and other drugs ;
• patients who received preoperative radiotherapy and chemotherapy;
• Patients with hypothyroidism, Parkinson's disease, stroke and other diseases.

Sponsors & Collaborators

• Zunyi Medical College: lead

Study Sites (1)

Yongmei Zhang

Zunyi, Guizhou, 563000, China

RECRUITING

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Study Officials

• Yongmei Zhang

  Zunyi Medical College

  STUDY DIRECTOR

Central Study Contacts

Yongmei Zhang

CONTACT

13885257269; hulizym@yeah.net

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Study Director

Study Record Dates

• First Submitted: May 19, 2023
• First Posted: May 30, 2023
• Study Start: August 1, 2022
• Primary Completion: July 31, 2025
• Study Completion: July 31, 2025
• Last Updated: May 30, 2023

Record last verified: 2023-05

Locations

CN (1)