Management of Sepsis in Resource Limited Settings Using a Delphi Method.

NCT05909384 | Completed

• 1 other identifier: APSADelphi_V1.2
• Study Type: observational
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

Rapid evolution of sepsis syndromes means that timely diagnosis and treatment are critical in improving outcomes but this may be difficult to achieve in many low- and middle- income countries (LMICs) and there is a lack of high quality clinical evidence to guide diagnosis and management in LMIC settings. The wide variability in health systems in LMICs means that additional areas of guidance may be required where staff or facilities are lacking. In the absence of clinical data, to address some of these issues, the investigators aim to use Delphi methodology to obtain experts consensus statements on some specific aspects of sepsis management in LMICs.

Conditions

Sepsis

Keywords

Sepsis; Septic shock; Low- and middle- income countries; LMIC; Delphi; Resource-limited setting

Outcome Measures

Primary Outcomes (1)

• Questionnaire statements which have reached pre-defined consensus

  Descriptive analysis of questionnaire statements which have reached pre-defined consensus. Consensus will be defined as \>70% participants in favour of agree/disagree statements (Likert scale 1-3 means disagree or 5-7 means agree), or \>80% in favour of single option in a single stem question with multiple responses (yes/no answers).

  2 weeks

Study Arms (1)

Expert group

1. Clinical expertise in adult sepsis management, AND 2. Demonstrated involvement with sepsis related research, educations, policy/protocols, professional activities

Other: Survey

Interventions

Survey OTHER

Multiple rounds of surveys collecting information on sepsis diagnosis and management in resource-limited settings.

Expert group

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants will be recognized experts meeting pre-defined criteria from a wide geographical distribution with approximately 70% from LMICs

You may qualify if:

• Recognized experts meeting pre-defined criteria (below) from a wide geographical distribution with approximately 70% from LMICs.
• Clinical expertise in adult sepsis management, AND
• Demonstrated involvement with sepsis related research, educations, policy/protocols, professional activities

Sponsors & Collaborators

• Oxford University Clinical Research Unit, Vietnam: lead
• Asia Pacific Sepsis Alliance: collaborator

Study Sites (1)

Oxford University Clinical Research Unit

Ho Chi Minh City, Vietnam

Location

MeSH Terms

Conditions

Sepsis; Shock, Septic

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Infections; Systemic Inflammatory Response Syndrome; Inflammation; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Shock

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Brett Abbenbroek, BSc,MPH,PhD

  The George Institute

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 19, 2023
• First Posted: June 18, 2023
• Study Start: May 16, 2023
• Primary Completion: August 21, 2023
• Study Completion: September 30, 2023
• Last Updated: January 19, 2024

Record last verified: 2024-01

Data Sharing

• IPD Sharing: Will not share

Locations

VN (1)