Health ImprOvement Program of Bone in China
1 other identifier
observational
5,000
1 country
1
Brief Summary
Fracture risk factors have long been identified as key factors in osteoporosis and fragility fractures. The WHO recommended Fracture risk assessmenttool (FRAX) applies clinical risk factors to assess the absolute risk of osteoporotic fractures in each individual. Our preliminary study suggests that FRAX estimates may underestimate the risk of fractures in the Chinese population. In order to optimize the risk prediction model of osteoporotic fractures, a treatment threshold and its optimal cutting point were initially established based on the data of the health management Center of the Second Xiangya Hospital of Central South University.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Feb 2021
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 27, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 27, 2021
CompletedFirst Submitted
Initial submission to the registry
June 7, 2023
CompletedFirst Posted
Study publicly available on registry
June 15, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
February 27, 2031
ExpectedJune 15, 2023
June 1, 2023
Same day
June 7, 2023
June 7, 2023
Conditions
Outcome Measures
Primary Outcomes (3)
bone mineral density bone mineral density
Bone mineral density (BMD) data measured by dual-energy X-ray absorptiometry were collected from patients over 40 years old
From 2021 to 2031
Occurrence of fracture
Follow-up of the population was conducted to track the incidence of fractures
From 2021 to 2031
clinical risk factors of osteoporotic fracture
The main clinical risk factors of osteoporotic fracture were collected
From 2021 to 2031
Interventions
Follow-up of the population was conducted to track the incidence of fractures
Eligibility Criteria
Dual-energy X-ray bone mineral density measurement was performed in the health management center of our hospital in the physical examination subjects over 40 years old
You may qualify if:
- Dual-energy X-ray bone mineral density measurement was performed in the health management center of our hospital in the physical examination subjects over 40 years old. Have independent civil capacity and agree to participate, and sign informed consent
You may not qualify if:
- Under 40 years of age， Patients who had undergone hip replacement or lumbar surgery and could not perform dual-energy X-ray BMD testing; Patients who have been treated with effective anti-osteoporosis drugs or have a history of malignant tumors.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Health Management Center, The Second Xiangya Hospital of Central South University
Changsha, Hunan, 410000, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Director of the Health Management Center of the Second Xiangya Hospital of Central South University
Study Record Dates
First Submitted
June 7, 2023
First Posted
June 15, 2023
Study Start
February 27, 2021
Primary Completion
February 27, 2021
Study Completion (Estimated)
February 27, 2031
Last Updated
June 15, 2023
Record last verified: 2023-06