Comparison of Conventional Versus Transverse Mini-Incision Technique for Carpal Tunnel Release

NCT07018011 | Completed

• 1 other identifier: DRKASHIFSAHIWAL
• Study Type: interventional
• Target: 46
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed at to fill the gaps by comparing the surgical outcomes of the conventional versus transverse mini-incision technique for carpal tunnel syndrome in terms of pain and functional outcomes.

Conditions

Carpal Tunnel Syndrome

Outcome Measures

Primary Outcomes (2)

• Pain severity

  A score percentage of 0-40 on the visual analog scale was graded as good, 50-60 as fair, and 70-100 as poor

  9 months

• Functional outcome

  On functional severity scale, a score percentage of 20-45% was graded as good, 46-60% was graded as fair, and 61-100% was graded as poor.

  9 months

Study Arms (2)

Conventional open CTR

EXPERIMENTAL

Conventional open CTR involved making a longitudinal incision in the wrist, typically along the median palmar crease, to access and release the transverse carpal ligament.

Procedure: Conventional open CTR

Transverse mini-incision technique

EXPERIMENTAL

Mini-incision CTR involved a smaller incision than traditional CTR procedures, aiming to minimize scarring and improve recovery time.

Procedure: Transverse mini-incision technique

Interventions

Conventional open CTR PROCEDURE

Conventional open CTR involved making a longitudinal incision in the wrist, typically along the median palmar crease, to access and release the transverse carpal ligament.

Conventional open CTR

Transverse mini-incision technique PROCEDURE

Mini-incision CTR involved a smaller incision than traditional CTR procedures, aiming to minimize scarring and improve recovery time.

Transverse mini-incision technique

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Any genders
• Aged between 18 and 70 years
• Presenting with symptoms of carpal tunnel syndrome for at least 3 months duration, and having a VAS score \> 4.

You may not qualify if:

• Patients with wrists with thenar atrophy
• Those who had previous CTR surgery
• Local injection for CTS
• Pregnant females
• Patients suffering from inflammatory arthropathy
• Polyneuropathy

Sponsors & Collaborators

• RESnTEC, Institute of Research: lead

Study Sites (1)

Sahiwal Teaching Hospital

Sahiwal, Punjab Province, 57000, Pakistan

Location

MeSH Terms

Conditions

Carpal Tunnel Syndrome

Condition Hierarchy (Ancestors)

Median Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries

Study Officials

• Kashif Raza, FCPS

  Sahiwal Teaching Hospital, Sahiwal

  PRINCIPAL INVESTIGATOR

• Muhammad Rashid, FCPS

  Sahiwal Teaching Hospital, Sahiwal

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 4, 2025
• First Posted: June 12, 2025
• Study Start: April 1, 2022
• Primary Completion: March 31, 2023
• Study Completion: March 31, 2023
• Last Updated: June 12, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)