NCT05904795

Brief Summary

The aim of this study is to evaluate the effects of proprioceptive neuromuscular facilitation strengthening exercises and de-Lorme and Watkins exercises program in stroke patients with upper limb weakness in chronic stroke patients. The randomized central trial will recruit patients according to consecutive sampling into two intervention groups. One group will receive proprioceptive neuromuscular facilitation strengthening exercises and other group will receive de-Lorme and Watkins exercises program.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 25, 2023

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

June 6, 2023

Completed
9 days until next milestone

First Posted

Study publicly available on registry

June 15, 2023

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 18, 2023

Completed
12 days until next milestone

Study Completion

Last participant's last visit for all outcomes

October 30, 2023

Completed
Last Updated

June 15, 2023

Status Verified

June 1, 2023

Enrollment Period

8 months

First QC Date

June 6, 2023

Last Update Submit

June 6, 2023

Conditions

Keywords

Proprioceptive neuromuscular facilitation

Outcome Measures

Primary Outcomes (2)

  • The barthel index scale

    The Barthel Index (BI) is a measure of independence in activities of daily living (ADL).It contains 10 components which has different scores.The total score is calculated by dividing 100.

    4th day

  • Hand held dynamometer

    The hand held dynamometry is an objective method in detecting minimum muscle strength change, which has an impact on the physical function of ICU survivors. The minimum change in the fore can be measured in units of weight such as pounds or kilograms.

    4th day

Study Arms (2)

PNF strengthening exercises

ACTIVE COMPARATOR

Pnf strengthening exercises along with isometrics and range of motion exercises

Other: PNF strengthening exercises

de-lorme and watkins progressive resistance exercises

ACTIVE COMPARATOR

progressive resistance exercises along with isometrics and range of motion exercises

Other: de-lorme and watkins exercises

Interventions

PNF strengthening exercises 10 repetitions, 1set , 4 days/week along with range of motion exercises total of 4 sessions were given consisting 40 minutes

PNF strengthening exercises

The group was given de-lorme and watkins progressive resistance exercises along with range of motion exercises .10 repetitions, 1set, 4 days /week along with range of motion exercises. total of 4 sessions per week each consisting of 40 minutes.

de-lorme and watkins progressive resistance exercises

Eligibility Criteria

Age50 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Chronic stroke patients.
  • Medically stable patients having a single stroke.
  • History of stroke 6 to 24 months.
  • A score greater than 24-30 in mini-mental test.
  • Patients having consciousness with GC;10

You may not qualify if:

  • Recurrent stroke
  • Patients with gullian berrie syndrome, multiple sclerosis lesion osteoarthritis of shoulder.
  • Manual muscle testing below grade II.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shahida Islam teaching hospital Lodhran

Lodhran, Punjab Province, 47541, Pakistan

RECRUITING

Related Publications (7)

  • Andrade SE, Harrold LR, Tjia J, Cutrona SL, Saczynski JS, Dodd KS, Goldberg RJ, Gurwitz JH. A systematic review of validated methods for identifying cerebrovascular accident or transient ischemic attack using administrative data. Pharmacoepidemiol Drug Saf. 2012 Jan;21 Suppl 1(Suppl 1):100-28. doi: 10.1002/pds.2312.

    PMID: 22262598BACKGROUND
  • Zuber M, Mas JL. [Epidemiology of cerebrovascular accidents]. Rev Neurol (Paris). 1992;148(4):243-55. French.

    PMID: 1439451BACKGROUND
  • Gillespie CD, Wigington C, Hong Y; Centers for Disease Control and Prevention (CDC). Coronary heart disease and stroke deaths - United States, 2009. MMWR Suppl. 2013 Nov 22;62(3):157-60.

    PMID: 24264507BACKGROUND
  • Mergenthaler P, Dirnagl U, Meisel A. Pathophysiology of stroke: lessons from animal models. Metab Brain Dis. 2004 Dec;19(3-4):151-67. doi: 10.1023/b:mebr.0000043966.46964.e6.

    PMID: 15554412BACKGROUND
  • Harris JE, Eng JJ. Paretic upper-limb strength best explains arm activity in people with stroke. Phys Ther. 2007 Jan;87(1):88-97. doi: 10.2522/ptj.20060065. Epub 2006 Dec 19.

    PMID: 17179441BACKGROUND
  • Hendricks HT, van Limbeek J, Geurts AC, Zwarts MJ. Motor recovery after stroke: a systematic review of the literature. Arch Phys Med Rehabil. 2002 Nov;83(11):1629-37. doi: 10.1053/apmr.2002.35473.

    PMID: 12422337BACKGROUND
  • Pak S, Patten C. Strengthening to promote functional recovery poststroke: an evidence-based review. Top Stroke Rehabil. 2008 May-Jun;15(3):177-99. doi: 10.1310/tsr1503-177.

    PMID: 18647724BACKGROUND

MeSH Terms

Conditions

Paresis

Condition Hierarchy (Ancestors)

Neurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Hira Jabeen, MSNMPT

    Riphah International Universiry

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Hira Jabeen, MSNMPT

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 6, 2023

First Posted

June 15, 2023

Study Start

February 25, 2023

Primary Completion

October 18, 2023

Study Completion

October 30, 2023

Last Updated

June 15, 2023

Record last verified: 2023-06

Data Sharing

IPD Sharing
Will not share

Locations