Acute Responses of Active Video Games and Traditional Exercise Program in in Patients With Pulmonary Hypertension

NCT05901168 | Completed

• 1 other identifier: DokuzEU-PAH-001
• Study Type: interventional
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

At least 20 volunteers with a diagnosis of Pulmonary Hypertension in the Department of Cardiology of Dokuz Eylul University and who meet the criteria for follow-up and inclusion will participate in the study. The aim of this study is to examine the acute effects of active video games compared to traditional exercise and the effects on energy expenditure and enjoyment in PH patients. Demographic and clinical information of the participants will be questioned. Active video games and home-based exercise sessions will be held randomly/by the same person with a break of at least 1 day in 1 week, lasting 20 minutes. Heart rate, blood pressure, shortness of breath and oxygen saturation will be measured before and after the sessions. In addition, energy expenditure, heart rate, perceived exertion, shortness of breath and oxygen saturation will be recorded during the sessions. In addition, arterial stiffness will be evaluated with a non-invasive device. At the end of the sessions, whether people like active video games or not will be questioned with a 10-point Likert-type scale.

Conditions

Pulmonary Hypertension

Keywords

pulmonary hypertension; active video games

Outcome Measures

Primary Outcomes (2)

• Exercise load end heart rate

  It will be measured with a pulse oximeter at the end of 20 minutes of exercise loading.

  Change from baseline to end of 20 minutes of exercise loading

• Exercise load end blood pressure

  It will be measured with a sphygmomanometer at the end of 20 minutes of exercise loading.

  Change from baseline to end of 20 minutes of exercise loading

Secondary Outcomes (5)

• Exercise load end perceived effort

  Change from baseline to end of 20 minutes of exercise loading

• Exercise load end oxygen saturation

  Change from baseline to end of 20 minutes of exercise loading

• Exercise load end shortness of breath

  Change from baseline to end of 20 minutes of exercise loading

• Evaluation of energy expenditure

  During exercise intervention, average 20 minutes

• Evaluation of Arterial stiffness

  Change from baseline to end of 20 minutes of exercise loading

Study Arms (2)

Active Video Games Intervention

ACTIVE COMPARATOR

Active video games intervention will be carried out with a virtual reality system (XBOX360, Microsoft, USA) consisting of a console and sensor. Active video games consist of Rally Ball, Rive Rush and Reflex Ridge games.

Other: Active Video Games Intervention

Traditional Exercise Intervention

ACTIVE COMPARATOR

Traditional Exercise Intervention consist of active exercises for the upper extremities, active exercises for the lower extremities, active exercises for the body.

Other: Traditional Exercise Intervention

Interventions

Active Video Games Intervention OTHER

Participants will complete active video games in the same order until they fill 20 minutes after the first 5 minutes of warm-up. In addition, during the change between games (lasting approximately 20 seconds), patients will be instructed by a therapist to perform combined exercises to minimize immobility time. These exercises are: elbow flexion and foot flexion, shoulder flexion and unilateral hip extension, and arm abduction and squat exercises that will prevent the patient from cooling down.

Active Video Games Intervention

Traditional Exercise Intervention OTHER

Active exercises for the upper extremities (without support): Shoulder flexion, Shoulder abduction, Elbow flexion at shoulder 90° flexion. Active exercises for the lower extremities: Ankle-foot movements (ankle pumping exercise), heel raise, Knee extension in sitting high, Hip-knee flexion while lying supine Body: Bridging, Trunk rotations in sitting These exercises will be done in 1 set of 8-10 repetitions. It will take about 20 minutes.

Traditional Exercise Intervention

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Have been diagnosed with PH
• Volunteering
• Being clinically stable
• New York Heart Association 1-3 class
• Have not received physiotherapy in the last 6 months

You may not qualify if:

• Presence of unstable angina
• Presence of severe neurological, pulmonary and musculoskeletal disease
• The patient's desire to quit the study
• Playing more than 20 minutes of active video games 3 days a week
• Pregnancy
• Having significant and uncompensated visual and auditory deficiencies

Sponsors & Collaborators

• Dokuz Eylul University: lead

Study Sites (1)

Dokuz Eylul University

Izmir, Balcova, 35140, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Hypertension, Pulmonary

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases; Hypertension; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Master of Science Student

Study Record Dates

• First Submitted: May 3, 2023
• First Posted: June 13, 2023
• Study Start: August 1, 2023
• Primary Completion: May 1, 2024
• Study Completion: May 30, 2024
• Last Updated: January 2, 2026

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)