NCT05892341

Brief Summary

Study is to provide evidence comparing AQUACEL® Ag+ Extra™ versus Cutimed® Sorbact® in the progression of wounds towards healing

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
203

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Dec 2022

Geographic Reach
3 countries

18 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 5, 2022

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

May 10, 2023

Completed
28 days until next milestone

First Posted

Study publicly available on registry

June 7, 2023

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 14, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 14, 2024

Completed
1.8 years until next milestone

Results Posted

Study results publicly available

December 2, 2025

Completed
Last Updated

December 2, 2025

Status Verified

December 1, 2025

Enrollment Period

1.2 years

First QC Date

May 10, 2023

Results QC Date

May 14, 2024

Last Update Submit

December 1, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Effectiveness of AQUACEL® Ag+ Extra™ and Cutimed® Sorbact® on Wound Management

    Complete wound closure as defined by 100% epithelialisation of the wound surface (Gould 2019)

    Up to 12 weeks

Secondary Outcomes (4)

  • Wound Healing Assessment

    Up to 4 weeks

  • Wound Progress Assessment

    Up to 4 weeks

  • Wound Change Assessment

    Up to 12 weeks

  • Safety Assesment

    Up to 12 weeks

Study Arms (2)

AQUACEL® Ag+ Extra™

ACTIVE COMPARATOR

AQUACEL® Ag+ Extra™ is approved, needle-bonded nonwoven fabric layered and stitch-bonded wound dressing

Device: AQUACEL® Ag+ Extra™

Cutimed® Sorbact®

ACTIVE COMPARATOR

Cutimed® Sorbact® is approved, bacterial and fungi binding wound dressing

Device: Cutimed® Sorbact®

Interventions

Wound treatment with AQUACEL® Ag+ Extra™ dressing

AQUACEL® Ag+ Extra™

Wound treatment with Cutimed® Sorbact® dressing

Cutimed® Sorbact®

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Venous insufficiency as defined by CEAP Classification of C6
  • One wound amendable to treatment with either AQUACEL® Ag+ Extra™ or Cutimed® Sorbact®
  • Wounds that have been present for at least 2 months
  • Reliable and available for follow-up
  • years or older
  • Able and willing to provide informed consent
  • Able to tolerate compression therapy for Venus Leg Ulcer
  • Must be able to be compliant with compression therapy

You may not qualify if:

  • Known sensitivities or allergies to components of the AQUACEL® Ag+ Extra™ or Cutimed® Sorbact®
  • Continued use of petroleum gel/ creams/ oil-based products
  • Active treatment for cancer or completed within the last 3 months
  • Documented severe malnutrition
  • Malignant wounds
  • Systemic infection actively treated with antibiotics

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (18)

Convatec Colombia Clinic

Barranquilla, Colombia

Location

Convatec Colombia Clinic

Bogotá, Colombia

Location

Convatec Colombia Clinic

Bucaramanga, Colombia

Location

Convatec Colombia Clinic

Cali, Colombia

Location

Convatec Colombia Clinic

Cartagena, Colombia

Location

Convatec Colombia Clinic

Medellín, Colombia

Location

Germany

Augsburg, Germany

Location

Germany

Berlin, Germany

Location

Germany

Bochum, Germany

Location

Germany

Düsseldorf, Germany

Location

Germany

Holzkirchen, Germany

Location

Germany

Ingolstadt, Germany

Location

Germany Clinic II

München, Germany

Location

Germany Clinic I

München, Germany

Location

Germany

Nuremberg, Germany

Location

Germany

Ratzeburg, Germany

Location

Germany

Rosenheim, Germany

Location

VCTC UK

Derby, United Kingdom

Location

MeSH Terms

Conditions

Varicose UlcerDiabetic Foot

Condition Hierarchy (Ancestors)

Varicose VeinsVascular DiseasesCardiovascular DiseasesLeg UlcerSkin UlcerSkin DiseasesSkin and Connective Tissue DiseasesDiabetic AngiopathiesFoot UlcerDiabetes ComplicationsDiabetes MellitusEndocrine System DiseasesDiabetic Neuropathies

Results Point of Contact

Title
Cristin Taylor, Senior Director, Medical Affairs, Advanced Wound Care
Organization
ConvaTec Inc.

Study Officials

  • Catarina Saavedra, MD

    Convatec Colombia Clinic

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 10, 2023

First Posted

June 7, 2023

Study Start

December 5, 2022

Primary Completion

February 14, 2024

Study Completion

February 14, 2024

Last Updated

December 2, 2025

Results First Posted

December 2, 2025

Record last verified: 2025-12

Data Sharing

IPD Sharing
Will not share

Locations