Triage of Patients With Acute Ischemic Stroke Due to Large Vessel Occlusions-1 (TRACK-LVO-1)
TRACK-LVO-1
1 other identifier
observational
5,000
1 country
1
Brief Summary
The aim of this study is to establish an academic, real-world, single-center, observational registry of consecutive patients hospitalized with acute ischemic stroke (AIS) due to large vessel occlusions (LVO), treated with either endovascular therapy (EVT) or best medical management (BMM).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2018
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2021
CompletedFirst Submitted
Initial submission to the registry
May 23, 2023
CompletedFirst Posted
Study publicly available on registry
June 1, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2025
CompletedNovember 29, 2023
November 1, 2023
3.8 years
May 23, 2023
November 28, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Modified ranking scale (mRS) at 90 days
A 0-6 scale running from perfect health without symptoms to death.
90 days
Mortality within 90 days
mortality of any causes.
90 days
Secondary Outcomes (3)
National Institutes of Health Stroke Scale (NIHSS) scores at 90 days
90 days
Occurrence of periprocedural complications
14 days postoperatively
ASPECT score (Alberta Stroke Program Early CT score)
Day 0
Study Arms (2)
Endovascular therapy
Timely thrombectomy for acute ischemic stroke patients with large vessel occlusion by either stent retriever, thrombus aspiration, others, or combination methods.
Best medical management
Patients enrolled in this group received the best medical management.
Interventions
Endovascular therapy, as an adjunct to standard stroke therapy, may be beneficial for a very select population of patients who present with an acute ischemic stroke and have a proven large, proximal occlusion on imaging. Endovascular therapy includes any one or more of the following: Intra-arterial thrombolytic therapy, aspiration, stent retrieval, or a combination of multiple mechanical devices.
Eligibility Criteria
Patients with acute ischemic stroke due to large vessel occlusion.
You may qualify if:
- Patient admitted from Jan. 1st, 2018 to June. 1st, 2021;
- Age ≥ 18;
- Ischemic stroke confirmed by head CT or MRI;
- Large vessel occlusion confirmed by head CTA or MRA: intracranial internal carotid artery (ICA), middle cerebral artery (MCA M1/M2), anterior cerebral artery (ACA A1/A2), basilar artery (BA), vertebral artery (VA), and posterior cerebral artery (PCA P1/P2);
- Patients receiving either endovascular therapy or best medical treatment;
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Tianjin Huanhu Hospital
Tianjin, Tianjin Municipality, 300222, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Chief Physician
Study Record Dates
First Submitted
May 23, 2023
First Posted
June 1, 2023
Study Start
January 1, 2018
Primary Completion
November 1, 2021
Study Completion
January 1, 2025
Last Updated
November 29, 2023
Record last verified: 2023-11