Triage of Patients With Acute Ischemic Stroke Due to Large Vessel Occlusions-2
TRACK-LVO-2
1 other identifier
observational
5,000
1 country
4
Brief Summary
The objective of this study is to create a comprehensive, real-world, multi-center observational registry of consecutive patients admitted to hospitals with acute ischemic stroke (AIS) caused by large vessel occlusions (LVO), who are treated with either endovascular therapy (EVT) or the best available medical management (BMM).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2021
Longer than P75 for all trials
4 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 1, 2021
CompletedFirst Submitted
Initial submission to the registry
December 13, 2022
CompletedFirst Posted
Study publicly available on registry
December 21, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2028
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 31, 2028
December 1, 2023
November 1, 2023
7.2 years
December 13, 2022
November 28, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Modified ranking scale (mRS) at 90 days
A 0-6 scale running from perfect health without symptoms to death.
90 days
Mortality within 90 days
mortality of any causes.
90 days
Secondary Outcomes (4)
National Institutes of Health Stroke Scale (NIHSS) scores at 90 days
90 days
Occurrence of periprocedural complications
14 days postoperatively
ASPECT (Alberta Stroke Program Early CT score)
Day 0
EuroQol five dimensions questionnaire (EQ-5D)
1 year
Study Arms (2)
Endovascular therapy
Timely thrombectomy for acute ischemic stroke patients with large vessel occlusion by either stent retriever, thrombus aspiration, others, or combination methods.
Best medical management
Patients enrolled in this group received the best medical management.
Interventions
Endovascular therapy, as an adjunct to standard stroke therapy, may be beneficial for a very select population of patients who present with an acute ischemic stroke and have a proven large, proximal occlusion on imaging. Endovascular therapy includes any one or more of the following: Intra-arterial thrombolytic therapy, aspiration, stent retrieval, or a combination of multiple mechanical devices.
Eligibility Criteria
All acute ischemic stroke patients with large vessel occlusion.
You may qualify if:
- Patient admitted from Jan. 1st 2018 to Jan. 1st 2028;
- Age ≥ 18;
- Ischemic stroke confirmed by head CT or MRI;
- Large vessel occlusion confirmed by head CTA or MRA: intracranial internal carotid artery (ICA), middle cerebral artery (MCA M1/M2), anterior cerebral artery (ACA A1/A2), basilar artery (BA), vertebral artery (VA), and posterior cerebral artery (PCA P1/P2);
- Patients receiving either endovascular therapy or best medical treatment;
You may not qualify if:
- \- None
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (4)
Tianjin Medical University General Hospital
Tianjin, Tianjin Municipality, 300052, China
The Sencond Hospital of Tianjin Medical University
Tianjin, Tianjin Municipality, 300211, China
Tianjin Huanhu Hospital
Tianjin, Tianjin Municipality, 300222, China
Beijing University Binhai Hospital
Tianjin, Tianjin Municipality, 300450, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 1 Year
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Chief Physician
Study Record Dates
First Submitted
December 13, 2022
First Posted
December 21, 2022
Study Start
November 1, 2021
Primary Completion (Estimated)
December 31, 2028
Study Completion (Estimated)
December 31, 2028
Last Updated
December 1, 2023
Record last verified: 2023-11