NCT05884034

Brief Summary

The purpose of this study is to evaluate the effects of a self-care educational program via telerehabilitation on the quality of life, burden, stress, pain, and depression of caregivers of people with ALS.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
22

participants targeted

Target at below P25 for not_applicable quality-of-life

Timeline
Completed

Started Jun 2023

Shorter than P25 for not_applicable quality-of-life

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 18, 2023

Completed
14 days until next milestone

First Posted

Study publicly available on registry

June 1, 2023

Completed
Same day until next milestone

Study Start

First participant enrolled

June 1, 2023

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2023

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2023

Completed
Last Updated

June 1, 2023

Status Verified

May 1, 2023

Enrollment Period

4 months

First QC Date

May 18, 2023

Last Update Submit

May 29, 2023

Conditions

Keywords

CaregiverCaregiver BurdenTelemedicine

Outcome Measures

Primary Outcomes (1)

  • Change in caregiver burden score measured through Zarit scale

    Measured through Zarit scale. The analyzed variable will be the score obtained from 22 questions scored on a 5-point Likert scale, from 0 (never) to 4 (nearly always)

    Baseline, immediately after the intervention protocol, and after 4 weeks after treatment

Secondary Outcomes (8)

  • Change in quality of life score measured through World Health Organization Quality of Life-100 (WHOQOL-BREF)

    Baseline, immediately after the intervention protocol, and after 4 weeks after treatment

  • Change in pain score measured through McGill Pain Questionnaire

    Baseline, immediately after the intervention protocol, and after 4 weeks after treatment

  • Change in stress score measured through Perceived Stress Scale (PSS)

    Baseline, immediately after the intervention protocol, and after 4 weeks after treatment

  • Change in depressive symptoms evaluated through Beck Depression Inventory

    Baseline, immediately after the intervention protocol, and after 4 weeks after treatment

  • Change in night awakenings measured through Sênior Saúde Móvel platform

    Baseline, daily during the entire intervention protocol, and after 4 weeks after treatment

  • +3 more secondary outcomes

Study Arms (2)

Telerehabilitation group

EXPERIMENTAL

Self-care educational program via telerehabilitation

Other: Telerehabilitation

Education group

ACTIVE COMPARATOR

Self-care educational program via informative booklet

Other: Education

Interventions

Subjects will participate in a six-week self-care education program with weekly synchronous meetings using Google Meet or WhatsApp and an informative booklet containing guidelines for performing physical activities at home and information on healthy eating, mental health and routine management, with a schedule for weekly organization.

Telerehabilitation group

Participants will receive an informative booklet containing guidelines for performing physical activities at home and information on healthy eating, mental health and routine management, with orientations on the importance of reading and implementing the guidelines described in the booklet.

Education group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Informal caregiver (i.e., family member, friend, or a caregiver without payment) of an individual with ALS (clinically defined, probable, or possible) diagnosed by a neurologist using the (El Escorial Criteria);
  • Informal caregiver of people who did not have any other neurological disease associated with ALS;
  • Aged 18 years or above;
  • Without cognitive impairment on the Mini-Mental State Examination (MMSE; cutoff point of 25 for literate individuals) for understanding the study and the informed consent form;
  • Literate (at least complete primary education).

You may not qualify if:

  • Health conditions that hinder from exercising safely, such as recent surgeries, fractures; uncontrolled heart, vascular and respiratory disorders; dizziness or vertigo, fainting; oncological diseases; neurological diseases that affect balance and protective reactions;
  • Caregivers in the first trimester of pregnancy, due to the risk of the sudden increase in resting heart rate;
  • Using psychiatric medication, such as anxiolytics, antidepressants, antipsychotics, and antiepileptics, as the use of these medications may interfere with the results of this study;
  • Drop out of two or more consecutive days without replacement

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Federal University of Rio Grande do Norte

Natal, Rio Grande do Norte, 59078-970, Brazil

Location

Related Publications (1)

  • Gomes de Souza E Silva EM, Tomaz da Silva S, Januario de Holanda L, Tezoni Borges D, Mendonca Fernandes AP, Evangelista Rodrigues da Silva K, Souza Ribeiro T, Protasio de Melo L, de Medeiros Valentim RA, Alves Pinto Nagem D, Rodrigues Lindquist AR. Effects of a self-care educational program via telerehabilitation on quality of life and caregiver burden in amyotrophic lateral sclerosis: a single-blinded randomized clinical trial protocol. Front Psychol. 2023 Aug 17;14:1164370. doi: 10.3389/fpsyg.2023.1164370. eCollection 2023.

MeSH Terms

Conditions

Caregiver Burden

Interventions

TelerehabilitationEducational Status

Condition Hierarchy (Ancestors)

Stress, PsychologicalBehavioral SymptomsBehavior

Intervention Hierarchy (Ancestors)

RehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsHealth ServicesHealth Care Facilities Workforce and ServicesTelemedicineDelivery of Health CarePatient Care ManagementHealth Services AdministrationSocioeconomic FactorsPopulation Characteristics

Study Officials

  • Ana R Lindquist, PhD

    Universidade Federal do Rio Grande do Norte

    STUDY CHAIR

Central Study Contacts

Ana R Lindquist, PhD

CONTACT

Daniel T Borges, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research group leader

Study Record Dates

First Submitted

May 18, 2023

First Posted

June 1, 2023

Study Start

June 1, 2023

Primary Completion

October 1, 2023

Study Completion

December 1, 2023

Last Updated

June 1, 2023

Record last verified: 2023-05

Locations