NCT05882942

Brief Summary

Intake of the green tea catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition. This research will expand the insight on the effects by Matcha green tea supplementation and address the effects on heart rate variability, substrate oxidation at rest, and cardiovascular responses at rest in addition to metabolic and physiologic responses for a 1-hr walk in healthy females.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
8

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 3, 2023

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

May 17, 2023

Completed
14 days until next milestone

First Posted

Study publicly available on registry

May 31, 2023

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 26, 2023

Completed
20 days until next milestone

Study Completion

Last participant's last visit for all outcomes

August 15, 2023

Completed
Last Updated

May 8, 2024

Status Verified

May 1, 2024

Enrollment Period

5 months

First QC Date

May 17, 2023

Last Update Submit

May 7, 2024

Conditions

No Condition

Outcome Measures

Primary Outcomes (6)

  • Heart rate variability

    Measurement of root mean square of standard deviation of RR intervals

    Three weeks

  • Carbohydrate oxidation

    Measurement of carbohydrate oxidation in grams/minute

    Three weeks

  • Fat oxidation

    Measurement of fat oxidation in grams/minute

    Three weeks

  • Cardiac output

    Measurement of cardiac output in liters per minute

    Three weeks

  • Stroke volume

    Measurement of stroke volume in milliliters

    Three weeks

  • Total peripheral resistance

    Measurement of total peripheral resistance in (mmHg x min) / mL

    Three weeks

Study Arms (2)

Placebo

EXPERIMENTAL

Participants will be supplemented with a placebo.

Dietary Supplement: Placebo

Matcha green tea

EXPERIMENTAL

Participants will be supplemented with Matcha green tea.

Dietary Supplement: Matcha green tea

Interventions

Matcha green teaDIETARY_SUPPLEMENT

This is the condition with the Matcha green tea

Matcha green tea
PlaceboDIETARY_SUPPLEMENT

This is the condition with the placebo

Placebo

Eligibility Criteria

Age18 Years - 30 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • healthy
  • non-smokers
  • not taking any supplements
  • no known allergy to green tea

You may not qualify if:

  • smokers
  • known high blood pressure
  • on medication

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Mark Willems

Chichester, West Sussex, PO19 6PE, United Kingdom

Location

University of Chichester

Chichester, United Kingdom

Location

Study Officials

  • Mark E Willems

    University of Chichester

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Model Details: Randomized, placebo-controlled, crossover design
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Exercise Physiology

Study Record Dates

First Submitted

May 17, 2023

First Posted

May 31, 2023

Study Start

March 3, 2023

Primary Completion

July 26, 2023

Study Completion

August 15, 2023

Last Updated

May 8, 2024

Record last verified: 2024-05

Data Sharing

IPD Sharing
Will not share

Locations

GB(2)