Validation of the Global Polypectomy Assessment Tool (GPAT)

NCT05877456 | Enrolling By Invitation

• 1 other identifier: ONZ-2022-0597
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Colorectal polypectomy is offten incompletely performed with high variability between endoscopists, resulting in interval cancer or repeated procedures. Current available scoring systems for polypectomy technique are lacking in different areas so the investigators developed the Global Polypectomy Assessment Tool (GPAT) which is an online video-based assessment tool for any colorectal polypectomy. The goal of the study is to assess the validity of GPAT through demonstrating the inter-rater agreement (Fleiss Kappa (κ)). GPAT has 20 items, contains evidence-based statements to aid interpretation, calculates an overall quality score and a complexity score.

Conditions

Colorectal Adenoma; Colorectal Polyp; Colo-rectal Cancer

Keywords

colonoscopy; polypectomy; quality in endoscopy

Outcome Measures

Primary Outcomes (1)

• To validate the GPAT (global polypectomy assesment tool) scoring tool for polypectomy using key performance indicators.

  Two scores are generated by this tool. The first score provides an indication on the quality of the polypectomy. This comprises of 6 domains: global competencies, injection, snare placement, safety checks, defect assessment, accessory techniques. The second score gives an indication on the difficulty of the polypectomy based upon the difference between the complexity of the assessed procedure and the maximum possible complexity (Size, morphology, site, access and 4 plus criteria: Size \> 40mm, non granular morfology, non lifting polyp/previously attempted, ileocaecal valve, diverticular or appendiceal orifice involvement). If some categories or questions are not relevant, it does not affect the score. The number of questions per category differs as well as the possible answers for each question. The score-system is web-based. The maximum score for the first part of the tool is 105. For the indication on the difficulty of the polypectomy the maximum score is 17.

  up to 1 year

Eligibility Criteria

• Age: 18 Years - 100 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Endoscopists of varying abilities and grades Adult patients undergoing a polypectomy who agree to participate

You may qualify if:

• Endoscopists of varying abilities and grades
• Adult patients undergoing a polypectomy who agree to participate

You may not qualify if:

• Patients \<18 y

Sponsors & Collaborators

• University Hospital, Ghent: lead

Study Sites (1)

uz Gent

Ghent, Gent, 9000, Belgium

Location

Related Publications (1)

• Smeets S, Argenziano ME, De Crem AC, Desomer L, Anderson J, Bhandari P, Boskoski I, Bugajski M, Bourke MJ, Debels L, Heitman SJ, Kashida H, Lee RRT, Lyutakov I, Rivero-Sanchez L, Schoonjans C, Thomas-Gibson S, Thorlacius H, Fuccio L, Tham TC, Bisschops R, Tate DJ. Validation of the GPAT - the Global Polypectomy Assessment Tool: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement. Endoscopy. 2025 May;57(5):555-566. doi: 10.1055/a-2541-4028. Epub 2025 Mar 14.

  PMID: 40086890 DERIVED

MeSH Terms

Conditions

Colonic Neoplasms

Condition Hierarchy (Ancestors)

Colorectal Neoplasms; Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 17, 2023
• First Posted: May 26, 2023
• Study Start: March 1, 2023
• Primary Completion (Estimated): March 1, 2027
• Study Completion (Estimated): March 2, 2027
• Last Updated: June 20, 2024

Record last verified: 2024-06

Locations

BE (1)