NCT05872646

Brief Summary

Parkinson's Disease (PD), first described by James Parkinson in 1817, is a progressive movement disorder that develops mainly as a result of the destruction of nigrostriatal dopaminergic neurons. The aim of our study is to determine the effect of cognitive functions on upper extremity functionality in individuals with Parkinson's Disease.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
104

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 8, 2018

Completed
5.1 years until next milestone

First Submitted

Initial submission to the registry

March 10, 2023

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 10, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 10, 2023

Completed
3 months until next milestone

First Posted

Study publicly available on registry

May 24, 2023

Completed
Last Updated

May 24, 2023

Status Verified

May 1, 2023

Enrollment Period

5.1 years

First QC Date

March 10, 2023

Last Update Submit

May 14, 2023

Conditions

ParkinsonCognitive ImpairmentUpper Extremity ProblemFunctional Disturbance

Keywords

ParkinsonCognitive functionUpper extremity

Outcome Measures

Primary Outcomes (3)

  • Modified Hoehn Yahr Scale

    Used for clinical staging of Parkinson's disease

    1 year

  • Unified Parkinson's Disease Rating Scale

    Used for the evaluation of clinical manifestations of Parkinson's disease

    1 year

  • Parkinson's Disease Questionnaire-PDQ 39

    Used to assess the quality of life of Parkinson's patients

    1 year

Secondary Outcomes (4)

  • Stroop Test

    1 year

  • Wechsler Memory Scale-Revised

    1 year

  • Dexterity Questionnaire-24

    1 year

  • Nine Hole Peg Test

    1 year

Study Arms (2)

patient group

EXPERIMENTAL

parkınson patient group

Diagnostic Test: clinical assessment

healthy group

OTHER

age-gender matched healthy group

Diagnostic Test: clinical assessment

Interventions

clinical assessmentDIAGNOSTIC_TEST

clinical staging

Also known as: modifiye hoehn yahr
healthy grouppatient group

Eligibility Criteria

Age30 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Having a diagnosis of Parkinson's Disease.
  • Not having hearing and vision problems.
  • To be able to take the commands required for the manual dexterity tests.
  • Agree to participate in the study.

You may not qualify if:

  • Having undergone musculoskeletal surgery for the upper extremity.
  • Having vision and hearing problems.
  • Having an additional disease that may affect cognitive tests.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pamukkale Unıversity

Denizli, 20000, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition DisordersNeurocognitive DisordersMental Disorders

Study Officials

  • DUDU ŞIMŞEK

    PhD student

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: patient and age-gender matched healthy groups
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MSc Physiotherapist

Study Record Dates

First Submitted

March 10, 2023

First Posted

May 24, 2023

Study Start

February 8, 2018

Primary Completion

March 10, 2023

Study Completion

March 10, 2023

Last Updated

May 24, 2023

Record last verified: 2023-05

Locations

TU(1)