Genital Wart and Sexuality in Adolescence

NCT04796090 | Completed

• 1 other identifier: E1-20-1000
• Study Type: observational
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

The adolescence is a landmark in perceiving the sexuality and awareness about the sexual experiences. Genitals warts were shown to be a potential risk to impair the sexual functions in women. Adolescence is a vulnerable period in which the individuals may be prone to the negative effects of the disorders affecting sexual functions such as genital warts. The current study aimed to investigate the impact of genital warts on sexual functions in female adolescents.

Conditions

Adolescent Development; Genital Wart; Sexual Dysfunction; Sexual Disorder, Physiological

Keywords

Genital wart; Female sexual dysfunction; Late adolescence; Sexuality related distress

Outcome Measures

Primary Outcomes (1)

• Female Sexual Function Index

  Questionnaire score with minimum and maximum levels of 2.4 and 36 points,respectively. Higher scores mean a better outcome.

  Through study completion, an average of 6 months

Secondary Outcomes (2)

• Arizona Sexual Experiences Scale

  Through study completion, an average of 6 months

• Female Sexual Distress Scale-Revised

  Through study completion, an average of 6 months

Study Arms (2)

Adolescents with genital warts (Study Group)

The Study group included adolescents who was diagnosed as positive for genital warts during the examination.

Other: Clinical assessment

Healthy adolescents (Control Group)

The Control group was composed of healthy adolescents who admitted for only contraceptive counselling.

Other: Clinical assessment

Interventions

Clinical assessment OTHER

FSFI, ASEX and FSDS scores were compared between the adolescents with (Study group) or without (Control group) genital warts.

Adolescents with genital warts (Study Group); Healthy adolescents (Control Group)

Eligibility Criteria

• Age: 17 Years - 21 Years
• Gender Eligibility Details: The study is aimed to elucidate female adolescents' sexual functions.
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The current study included 45 adolescents with the diagnosis of genital warts as the Study group and 45 healthy adolescents as the Control group.

You may qualify if:

• The Study group included adolescents who was diagnosed as positive for genital warts during the examination.
• The Control group was composed of healthy adolescents who admitted for contraceptive counselling.

You may not qualify if:

• Chronical disease including rheumatological diseases, renal failure, diabetes mellitus, hypertension, dyslipidemia, obesity, thyroid dysfunction, cardiopulmonary diseases, malignancy, cerebrovascular diseases, psychiatric and mental disorders, cerebrovascular diseases, inflammatory bowel diseases.
• Drug administration which may interfere sexual function.
• Surgical intervention to genital organs.
• History of pregnancy, delivery, and/or breastfeeding.

Sponsors & Collaborators

• Ankara City Hospital Bilkent: lead

Study Sites (1)

Ankara City Hospital

Ankara, 06100, Turkey (Türkiye)

Location

Related Publications (7)

• Graziottin A, Serafini A. HPV infection in women: psychosexual impact of genital warts and intraepithelial lesions. J Sex Med. 2009 Mar;6(3):633-45. doi: 10.1111/j.1743-6109.2008.01151.x. Epub 2009 Jan 13.

  PMID: 19170869 RESULT

• McCabe MP, Sharlip ID, Atalla E, Balon R, Fisher AD, Laumann E, Lee SW, Lewis R, Segraves RT. Definitions of Sexual Dysfunctions in Women and Men: A Consensus Statement From the Fourth International Consultation on Sexual Medicine 2015. J Sex Med. 2016 Feb;13(2):135-43. doi: 10.1016/j.jsxm.2015.12.019.

  PMID: 26953828 RESULT

• McGahuey CA, Gelenberg AJ, Laukes CA, Moreno FA, Delgado PL, McKnight KM, Manber R. The Arizona Sexual Experience Scale (ASEX): reliability and validity. J Sex Marital Ther. 2000 Jan-Mar;26(1):25-40. doi: 10.1080/009262300278623.

  PMID: 10693114 RESULT

• Rosen R, Brown C, Heiman J, Leiblum S, Meston C, Shabsigh R, Ferguson D, D'Agostino R Jr. The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther. 2000 Apr-Jun;26(2):191-208. doi: 10.1080/009262300278597.

  PMID: 10782451 RESULT

• Greydanus DE, Matytsina L. Female sexual dysfunction and adolescents. Curr Opin Obstet Gynecol. 2010 Oct;22(5):375-80. doi: 10.1097/GCO.0b013e32833d9418.

  PMID: 20706119 RESULT

• Derogatis L, Clayton A, Lewis-D'Agostino D, Wunderlich G, Fu Y. Validation of the female sexual distress scale-revised for assessing distress in women with hypoactive sexual desire disorder. J Sex Med. 2008 Feb;5(2):357-64. doi: 10.1111/j.1743-6109.2007.00672.x. Epub 2007 Nov 27.

  PMID: 18042215 RESULT

• O'Sullivan LF, Byers ES, Brotto LA, Majerovich JA, Fletcher J. A Longitudinal Study of Problems in Sexual Functioning and Related Sexual Distress Among Middle to Late Adolescents. J Adolesc Health. 2016 Sep;59(3):318-324. doi: 10.1016/j.jadohealth.2016.05.001. Epub 2016 Jun 16.

  PMID: 27320034 RESULT

MeSH Terms

Conditions

Condylomata Acuminata; Sexual Dysfunction, Physiological

Condition Hierarchy (Ancestors)

Papillomavirus Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Communicable Diseases; Infections; DNA Virus Infections; Virus Diseases; Warts; Skin Diseases, Viral; Tumor Virus Infections; Genital Diseases; Urogenital Diseases; Skin Diseases, Infectious; Skin Diseases; Skin and Connective Tissue Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Esin Merve Erol Koç, MD

  Ankara City Hospital Bilkent

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: March 10, 2021
• First Posted: March 12, 2021
• Study Start: August 1, 2020
• Primary Completion: February 1, 2021
• Study Completion: February 15, 2021
• Last Updated: March 15, 2021

Record last verified: 2021-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)