Acute Ischemic Stroke EndoVascular Therapy: a Multicenter REGISTRY Study
1 other identifier
observational
10,000
1 country
1
Brief Summary
A Multicenter Registry of Endovascular Treatment for Acute Ischemic Stroke.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started May 2023
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 13, 2023
CompletedStudy Start
First participant enrolled
May 10, 2023
CompletedFirst Posted
Study publicly available on registry
May 18, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 30, 2028
ExpectedStudy Completion
Last participant's last visit for all outcomes
August 31, 2028
January 27, 2025
January 1, 2025
5.3 years
April 13, 2023
January 23, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Functional outcome
Shift (improvement) in scores on the modified Rankin scale (mRS) at 90 days (±7 days). The value range 0-6: higher scores mean a worse outcome.
90days
Secondary Outcomes (6)
Dichotomized modified Rankin scale (mRS)
90days
NIHSS at 24 hours
24 hours post-procedure
NIHSS at 7 days
7 days post procedure
Reperfusion outcome
Immediately post-procedure
Early successful revascularization rate
During procedure
- +1 more secondary outcomes
Other Outcomes (5)
Death
7 days and 90 days
Intracerebral hemorrhage(ICH)
90 days
Procedure related complication
within 30 days after procedure
- +2 more other outcomes
Study Arms (1)
Endovascular treatment
Interventions
Endovascular treatment, such as mechanical thrombectomy with stent, aspiration catheter or stent assisted by intermediate aspiration catheter, as well as combination of mechanical thrombectomy with intra-arterial thrombolysis
Eligibility Criteria
All acute ischemic stroke patients receiving endovascular treatment
You may qualify if:
- Acute ischemic stroke caused by anterior or posterior circulation vessel occlusion confirmed by computed tomography angiography (CTA) or magnetic resonance angiography (MRA) or digital subtraction angiography (DSA)
- Undergo intravascular therapy (i.e. access to a cath lab and an arterial puncture)
- The patient or his/her legal representative agreed to participate in the study and has signed the informed consent.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Jianimin Liu
Shanghai, China
Biospecimen
thrombus
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jianimin Liu, M.D.
Changhai Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 90 Days
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Director of Cerebrovascular Disease Center
Study Record Dates
First Submitted
April 13, 2023
First Posted
May 18, 2023
Study Start
May 10, 2023
Primary Completion (Estimated)
August 30, 2028
Study Completion (Estimated)
August 31, 2028
Last Updated
January 27, 2025
Record last verified: 2025-01
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP
- Time Frame
- Data sharing will be available from 12 months after the publication of the main results.
- Access Criteria
- 1. The data sharing will be only for the purposes of health and medical research and within the constraints of the consent under which the data were originally gathered. 2. The Custodian of the Collection will not consider any Proposals for data sharing that unblind, or potentially unblind, randomised comparisons in active / ongoing trials. 3. Requesters should be employees of a recognised academic institution, health service organisation, commercial research organisation or from the pharmaceutical industry. Requesters must have experience in medical research. 4. Requesters must be able to demonstrate through their peer review publications in the area of interest their ability to carry out the proposed use of the requested dataset from a Collection. 5. The Requesters must not have a conflict of interest that may potentially influence their interpretation of any analyses
Data can be shared with bona fide researchers after the publication of the main results, based on a submitted protocol to Oriental Collaboration group on Emerging Advanced therapy for Neurovascular diseases Consortium.